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Grade of Hydronephrosis and Tumor Diameter as Preoperative Prognostic Factors in Ureteral Transitional Cell Carcinoma

Authors
 Kang Su Cho  ;  Sung Joon Hong  ;  Young Deuk Choi  ;  Nam Hoon Cho 
Citation
 UROLOGY, Vol.70(4) : 662-666, 2007 
Journal Title
 UROLOGY 
ISSN
 0090-4295 
Issue Date
2007
Abstract
OBJECTIVES: To evaluate the clinical significance of the grade of hydronephrosis and the tumor diameter in ureteral transitional cell carcinoma. METHODS: From 1986 to 2004, the medical records of 104 patients who were treated with nephroureterectomy and diagnosed with ureteral transitional cell carcinoma were retrospectively reviewed. The correlation of the grade of hydronephrosis and tumor diameter with the pathologic T stage was investigated. Also evaluated were the effects of the grade of hydronephrosis and tumor diameter on the prognosis. RESULTS: The grade of hydronephrosis was grade 0 in 11 patients, grade 1 to 2 in 36, and grade 3 to 4 in 57. The tumor diameter measured on the transverse section of the computed tomography scan was less than 1.5 cm in 40 patients, 1.5 cm or greater but less than 2.5 cm in 37, and 2.5 cm or greater in 27 patients. Of the 57 patients with grade 3 to 4 hydronephrosis, invasive tumor was found in 49 (86.0%). Of the 64 patients with a tumor diameter of 1.5 cm or greater, invasive tumor was found in 51 (79.7%). The grade of hydronephrosis and the tumor diameter correlated with the T stage (P <0.001). In addition, the grade of hydronephrosis (P = 0.022) and the tumor diameter (P = 0.008) had a significant influence on disease-specific survival. CONCLUSIONS: The results of our study have demonstrated that the grade of hydronephrosis and the tumor diameter correlate with the pathologic T stage and have a significant influence on prognosis. Thus, radical surgery is required for patients with severe hydronephrosis or a large tumor diameter, rather than conservative surgery.
Full Text
http://www.sciencedirect.com/science/article/pii/S0090429507017852
DOI
10.1016/j.urology.2007.06.1106
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Cho, Kang Su(조강수) ORCID logo https://orcid.org/0000-0002-3500-8833
Cho, Nam Hoon(조남훈) ORCID logo https://orcid.org/0000-0002-0045-6441
Choi, Young Deuk(최영득) ORCID logo https://orcid.org/0000-0002-8545-5797
Hong, Sung Joon(홍성준) ORCID logo https://orcid.org/0000-0001-9869-065X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97438
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