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옥트레오타이드를 이용한 유육종증과 동반된 유미흉의 보존적 치료 1예

Other Titles
 A Case of Successful Management of Sarcoidosis with Chylothorax Using Octreotide 
Authors
 정경수  ;  문지애  ;  박무석  ;  김성규  ;  장준  ;  김세규  ;  김영삼  ;  표주연  ;  김대준  ;  최상봉  ;  정재희  ;  정우영  ;  변민광  ;  윤설희 
Citation
 Tuberculosis and Respiratory Diseases, Vol.62(2) : 119-124, 2007 
Journal Title
 Tuberculosis and Respiratory Diseases 
ISSN
 1738-3536 
Issue Date
2007
Abstract
Sarcoidosis is a multi-system granulomatous disorder of an unknown etiology and affects individuals worldwide. It is characterized pathologically by the presence of non-caseating granulomas in more than one involved organ. However, pleural involvement of sarcoidosis is rare and there are no reported cases in Korea. Traditionally, sarcoidosis has often been treated with systemic corticosteroids or cytotoxic agents. In particular, chylothorax with sarcoidosis is usually treated with corticosteroid for approximately 3~6 months, followed by repeated therapeutic thoracentesis, talc pleurodesis, dietary treatment, or thoracic duct ligation where needed. We encountered a 46 years old female patient presenting with cough, dyspnea and both hilar lymphadenopathy (stage I) on chest radiograph. The patient was diagnosed with a non-caseating granuloma, sarcoidosis by a mediastinoscopic biopsy. For one month, she had suffered from dyspnea due to right side pleural effusion, which was clearly identified as a chylothorax on thoracentesis. Corticosteroid therapy with dietary adjustment was ineffective. She was treated successfully with a subcutaneous injection of octreotide for 3 weeks and oral corticosteroid. We report a case of successful and rapid treatment of chylothorax associated with sarcoidosis using octreotide and oral corticosteroid.
Files in This Item:
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DOI
10.4046/trd.2007.62.2.119
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김성규(Kim, Sung Kyu)
김세규(Kim, Se Kyu)
김영삼(Kim, Young Sam) ORCID logo https://orcid.org/0000-0001-9656-8482
문지애(Moon, Ji Ae)
박무석(Park, Moo Suk) ORCID logo https://orcid.org/0000-0003-0820-7615
변민광(Byun, Min Kwang) ORCID logo https://orcid.org/0000-0003-1525-1745
윤설희(Yoon, Sul Hee)
장준(Chang, Joon) ORCID logo https://orcid.org/0000-0003-4542-6841
정경수(Jung, Kyung Soo) ORCID logo https://orcid.org/0000-0003-1604-8730
정우영(Jung, Woo Young)
정재희(Jung, Jae Hee)
최상봉(Choi, Sang Bong)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97424
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