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Immunohistochemical localization of 2-Cys peroxiredoxins in human ciliary body

Authors
 Samin Hong  ;  Chan Yun Kim  ;  Gong Je Seong  ;  Joon H. Lee 
Citation
 TISSUE & CELL, Vol.39(5) : 365-368, 2007 
Journal Title
 TISSUE & CELL 
ISSN
 0040-8166 
Issue Date
2007
Abstract
2-Cys peroxiredoxins (PRDX) are novel antioxidant enzymes that eliminate the hydrogen peroxide in cells to protect the cellular components from reactive oxygen species. To evaluate whether 2-Cys PRDX family plays a role in human ciliary body, the expression of PRDX I, II and III on normal human ciliary body was investigated. Three normal human ciliary body tissues obtained from three donor eyeballs were examined by an immunohistochemistry using light microscopy and fluorescent microscopy with antibodies directed against the PRDX I, II and III. In the normal human ciliary body, PRDX I, II and III were immunolocalized to the non-pigmented epithelial cells and ciliary muscle fibers. It suggests that 2-Cys PRDXs may have physiological functions to protect cells in human ciliary body.
Full Text
http://www.sciencedirect.com/science/article/pii/S0040816607000559
DOI
10.1016/j.tice.2007.06.003
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chan Yun(김찬윤) ORCID logo https://orcid.org/0000-0002-8373-9999
Seong, Gong Je(성공제) ORCID logo https://orcid.org/0000-0002-5456-4296
Hong, Sa Min(홍사민)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97400
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