Cited 12 times in
Molecular epidemiology of community-associated antimicrobial-resistant Staphylococcus aureus in Seoul, Korea (2003): Pervasiveness of multidrug-resistant SCCmec type II methicillin-resistant S. aureus
DC Field | Value | Language |
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dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2014-12-21T17:12:28Z | - |
dc.date.available | 2014-12-21T17:12:28Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1076-6294 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/97148 | - |
dc.description.abstract | There is an extremely high incidence of antimicrobial resistance of the clinical isolates of Staphylococcus aureus in Korea. This study carried out a molecular investigation to determine the prevalence of the community-associated antimicrobial-resistant S. aureus and methicillin-resistant S. aureus (MRSA). The percentage resistance from the nasal swabs of healthy volunteers in 2003 in Seoul is as follows: penicillin (91%), erythromycin (EM, 14%), gentamicin (GM, 9.3%), tetracycline (TE, 8.2%), cephalothin (4%), oxacillin (OX, MRSA; 3.8%), clindamycin (CC, 2.6%), ciprofloxacin (CIP, 0.8%), and sulfamethoxazole/trimethoprim (0.6%). The community-associated MRSA (C-MRSA) strains were examined by pulsed-field gel electrophoresis (PFGE) analysis of the SmaI macro-fragments, multilocus sequence typing (MLST), and staphylococcal cassette chromosome mec (SCCmec) typing using the PCR analysis. The Korean C-MRSA isolates were clustered into three distinct groups. One PFGE group containing the C-MRSA strains showed resistance to CC, EM, and GM, a high level (32-96 microg/ml) of resistance to methicillin, sequence type 5 (ST5), and SCCmec type II, which is the most common hospital associated-MRSA (H-MRSA) isolated in Korea. These results highlight the heterogeneous genetic background of the C-MRSA as well as the pervasiveness of the H-MRSA isolates in this community. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | MICROBIAL DRUG RESISTANCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Molecular epidemiology of community-associated antimicrobial-resistant Staphylococcus aureus in Seoul, Korea (2003): Pervasiveness of multidrug-resistant SCCmec type II methicillin-resistant S. aureus | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Jung-Eun Lee | - |
dc.contributor.googleauthor | Bo-Kyung Choi | - |
dc.contributor.googleauthor | Hye-Yoon Jeong | - |
dc.contributor.googleauthor | Kyung-Won Seo | - |
dc.contributor.googleauthor | Seung-Hee Park | - |
dc.contributor.googleauthor | Young-Lim Kim | - |
dc.contributor.googleauthor | Kyoung-Min Baek | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.contributor.googleauthor | Dong-Kwon Rhee | - |
dc.identifier.doi | 10.1089/mdr.2007.709 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J02229 | - |
dc.identifier.eissn | 1931-8448 | - |
dc.identifier.url | http://online.liebertpub.com/doi/abs/10.1089/mdr.2007.709 | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 13 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 178 | - |
dc.citation.endPage | 185 | - |
dc.identifier.bibliographicCitation | MICROBIAL DRUG RESISTANCE, Vol.13(3) : 178-185, 2007 | - |
dc.identifier.rimsid | 55206 | - |
dc.type.rims | ART | - |
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