패혈성 감염성 심내막염으로 개심술 후 발생한 vasoplegic syndrome에서 메틸렌 블루의 투여 후 혈압회복

Abstract

Vasoplegic syndrome occurs in 8∼10% of patients following cardiac surgery, and this happens in part because of inducing the inflammatory response. Nitric oxide and guanylate cyclase play an important role in this response, and this is associated with increased morbidity and mortality. For our case, we administered methylene blue (MB), an inhibitor of guanylate cyclase, early after performing cardiopulmonary bypass in a patient with vasoplegic syndrome. The patient recovered immediately after MB administration and maintained an optimal blood pressure without the aid help of any vasopressors.