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지속성 복막투석 환자에서 나타난 혈중 호산구증가증

Other Titles
 Blood Eosinophilia in Patients Undergoing Continous Ambulatory Peritoneal Dialysis 
Authors
 황혜진  ;  서원나  ;  한대석  ;  이호영  ;  최규헌  ;  강신욱  ;  김범석  ;  이정은  ;  이한성  ;  전성하  ;  전성완 
Citation
 Korean Journal of Nephrology, Vol.26(1) : 91-98, 2007 
Journal Title
 Korean Journal of Nephrology 
ISSN
 1225-0015 
Issue Date
2007
Abstract
Purpose: The prevalence of blood eosinophilia in patients who are maintained on regular hemodialysis has been well established. Blood eosinophilia in patients initiating peritoneal dialysis has been mentioned, but its prevalence and etiologic factors have not been well delineated. Therefore, we performed this retrospective study to find out prevalence and possible etiologic factors of blood eosinophilia in patients undergoing continuous ambulatory peritoneal dialysis. Methods: Between May 2001 to May 2004, the patients who began continuous ambulatory peritoneal dialysis at one renal center were included in this study. Patients with allergic history or allergic reaction during observed period were excluded. The routine peripheral WBC counts of 47 patients were reviewed and possible predisposing factors of eosinophilia were investigated. Results: Blood eosinophilia was observed in 17 of 47 patients (35% of all patients). In most patients with blood eosinophilia, the time in which the eosinophil count began to be rise was within 40 days, and duration of eosinophilia was variable (mean±SD;74±67 days). The mean of the peak eosinophil count was 750±257/mm3 (mean±SD). Possible predisposing factors included recent parenteral iron therapy, but not statistically significant (p=0.09). Conclusion: Our retrospective study showed that the eosinophil counts in patients with end stage renal disease on continuous ambulatory peritoneal dialysis were frequently elevated. Predisposing factors for this eosinophilia were not clear, suggesting that immunologic disturbance by uremia or dialysis itself might have influence on eosinophil homeostasis.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
강신욱(Kang, Shin Wook) ORCID logo https://orcid.org/0000-0002-5677-4756
김범석(Kim, Beom Seok) ORCID logo https://orcid.org/0000-0002-5732-2583
서원나(Suh, Won Na)
이정은(Lee, Jung Eun) ORCID logo https://orcid.org/0000-0003-0917-2872
이한성(Lee, Han Sung)
이호영(Lee, Ho Yung)
전성완(Chun, Sung Wan)
전성하(Cheon, Seong Ha)
최규헌(Choi, Kyu Hun) ORCID logo https://orcid.org/0000-0003-0095-9011
한대석(Han, Dae Suk)
황혜진(Hwang, Hye Jin)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96968
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