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Anti-PF4/Heparin 항체 양성의 헤파린 유도 혈소판감소증 1예

DC FieldValueLanguage
dc.contributor.author송경순-
dc.contributor.author송재우-
dc.date.accessioned2014-12-21T17:05:45Z-
dc.date.available2014-12-21T17:05:45Z-
dc.date.issued2007-
dc.identifier.issn1738-7949-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/96937-
dc.description.abstractHeparin-induced thrombocytopenia (HIT) is usually caused by anti-platelet factor 4 (PF4)/heparin antibodies, leading to intravascular platelet activation. Circulating anti-PF4/heaprin antibody (IgG, IgA and IgM) was detected by ELISA (Asserachrom HPIA, Diagnostia Stago, Asnieres, France) in a 61-year-old man with coronary artery disease and dyspnea on exercise. He had undergone a coronoary angiography using 2,000 unit of heparin before a procedure. On admission, laboratory testing revealed a platelet count of 296×109/L and aPTT (activated partial thromboplastin time) of 38.1 sec. The fall in the platelet count was progressive, resulting in 42% and 53% of platelet counts on the 6th and 12th days after intravenous heparin administration, respectively. He was discharged after coronary artery bypass graft. On discharge, platelet count was normalized to be 212×109/L. On the 7th day after dischage, anti-PF4/heaprin antibody was detected by ELISA (Asserachrom HPIA, Diagnostia Stago, Asnieres, France).-
dc.description.statementOfResponsibilityopen-
dc.format.extent67~70-
dc.relation.isPartOfKorean Journal of Hematology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAnti-PF4/Heparin 항체 양성의 헤파린 유도 혈소판감소증 1예-
dc.title.alternativeA Case of Heparin Induced Thrombocytopenia with Circulating Anti-PF4/Heparin Antibody-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthor송경순-
dc.contributor.googleauthor이양순-
dc.contributor.googleauthor송재우-
dc.contributor.googleauthor김주원-
dc.identifier.doi10.5045/kjh.2007.42.1.67-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02011-
dc.contributor.localIdA02054-
dc.relation.journalcodeJ02033-
dc.contributor.alternativeNameSong, Kyung Soon-
dc.contributor.alternativeNameSong, Jae Woo-
dc.contributor.affiliatedAuthorSong, Kyung Soon-
dc.contributor.affiliatedAuthorSong, Jae Woo-
dc.rights.accessRightsfree-
dc.citation.volume42-
dc.citation.number1-
dc.citation.startPage67-
dc.citation.endPage70-
dc.identifier.bibliographicCitationKorean Journal of Hematology, Vol.42(1) : 67-70, 2007-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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