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판막수술을 시행 받는 환자에서 레닌-안지오텐신계 길항제가 체외순환 후 요골-대퇴동맥압 간의 차이에 미치는 영향
DC Field | Value | Language |
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dc.contributor.author | 곽영란 | - |
dc.contributor.author | 방서욱 | - |
dc.contributor.author | 심재광 | - |
dc.contributor.author | 이종화 | - |
dc.date.accessioned | 2014-12-21T17:02:21Z | - |
dc.date.available | 2014-12-21T17:02:21Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/96826 | - |
dc.description.abstract | Background Femoral to radial arterial pressure gradient (ΔP) often develops after cardiopulmonary bypass (CPB) where radial artery pressure (RAP) does not reflect the actual perfusion pressure. Renin-angiotensin system antagonists (RAS-A) are increasingly prescribed preoperatively which causes vasodilation and vascular remodeling. We evaluated the effect of RAS-A medication on ΔP after CPB in patients undergoing valvular heart surgery. Methods Eighty-five patients scheduled for elective valvular heart surgery for regurgitant lesions were divided into two groups: the RAS-A group, in which patients were on RAS-A preoperatively (n = 52) and the control group (n = 33). Hemodynamic variables including RAP, femoral arterial pressure (FAP), body temperature, and hematocrit were recorded at after induction of anesthesia, pre-and post-CPB and sternum closure. Results After CPB, systolic ΔP was significantly greater in the RAS-A group than in the control group. Nine (27%) and 36 (69%) patients after CPB, and 6 (18%) and 23 (44%) patients after sternum closure developed systolic ΔP more than 10 mmHg, in the control and RAS-A group, respectively, which were statistically significant. Body temperature, hematocrit and systemic vascular resistance index were not different between groups. Conclusions Preoperative treatment with RAS-A resulted in clinically significant ΔP after cardiopulmonary bypass in about 70% of patients undergoing valvular heart surgery. Concomitant monitoring of FAP with RAP might be helpful to prevent inadequate vasopressor therapy guided by inaccurate RAP after CPB in this subset of patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 199~205 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF ANESTHESIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 판막수술을 시행 받는 환자에서 레닌-안지오텐신계 길항제가 체외순환 후 요골-대퇴동맥압 간의 차이에 미치는 영향 | - |
dc.title.alternative | Effect of Preoperative Renin-Angiotensin System Antagonists on the Difference between Radial and Femoral Arterial Pressure after Cardiopulmonary Bypass in Patients Undergoing Valvular Heart Surgery | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | 김대희 | - |
dc.contributor.googleauthor | 곽영란 | - |
dc.contributor.googleauthor | 방서욱 | - |
dc.contributor.googleauthor | 차재호 | - |
dc.contributor.googleauthor | 심재광 | - |
dc.contributor.googleauthor | 이종화 | - |
dc.identifier.doi | 10.4097/kjae.2007.53.2.199 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00172 | - |
dc.contributor.localId | A01785 | - |
dc.contributor.localId | A02205 | - |
dc.contributor.localId | A03154 | - |
dc.relation.journalcode | J03189 | - |
dc.identifier.eissn | 2005-7563 | - |
dc.contributor.alternativeName | Kwak, Young Lan | - |
dc.contributor.alternativeName | Bang, Sou Ouk | - |
dc.contributor.alternativeName | Shim, Jae Kwang | - |
dc.contributor.alternativeName | Lee, Jong Wha | - |
dc.contributor.affiliatedAuthor | Kwak, Young Lan | - |
dc.contributor.affiliatedAuthor | Bang, Sou Ouk | - |
dc.contributor.affiliatedAuthor | Shim, Jae Kwang | - |
dc.contributor.affiliatedAuthor | Lee, Jong Wha | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 53 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 199 | - |
dc.citation.endPage | 205 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.53(2) : 199-205, 2007 | - |
dc.identifier.rimsid | 36927 | - |
dc.type.rims | ART | - |
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