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Regeneration of Bone Defect Using Micro-Bioceramic PLLA Polymer Scaffolds Synthesized by Nonsolvent and Solvent Method
DC Field | Value | Language |
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dc.contributor.author | 이진우 | - |
dc.date.accessioned | 2014-12-21T17:00:30Z | - |
dc.date.available | 2014-12-21T17:00:30Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1013-9826 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/96768 | - |
dc.description.abstract | Poly-L-lactic acid (PLLA) is a desirable and very attractive polymer for fabricating porous scaffolds. As of now, a solvent casting method with organic solvents has been used in scaffold fabrication process. However, residual organic solvents in the scaffolds have the problems of decreasing the effect of osteogenic induction due to the hindrance of bioceramic by polymer solution and it’s harmfulness in vivo. To avoid these disadvantages of scaffolds by organic solvent casting method, we developed a new method fabricating polymer (PLLA)/ceramic (β -TCP) composite scaffolds by baking method without using solvent, and then we tested properties of scaffolds on animals. As the result, non-toxicity has been proved through animal experiment and newly fabricated polymer/ceramic composites by a novel sintering method were induced rapid bone regeneration through enhancing the interaction of cells and a bone induction factor without any host immune response. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 145~148 | - |
dc.relation.isPartOf | Key Engineering Materials | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Regeneration of Bone Defect Using Micro-Bioceramic PLLA Polymer Scaffolds Synthesized by Nonsolvent and Solvent Method | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Orthopedic Surgery (정형외과학) | - |
dc.contributor.googleauthor | Min Sung Park | - |
dc.contributor.googleauthor | Young Mee Jung | - |
dc.contributor.googleauthor | Jin Woo Lee | - |
dc.contributor.googleauthor | Byoung Goo Min | - |
dc.contributor.googleauthor | Young Ha Kim | - |
dc.contributor.googleauthor | Sang Heon Kim | - |
dc.contributor.googleauthor | Soo Hyun Kim | - |
dc.identifier.doi | 10.4028/www.scientific.net/KEM.342-343.145 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03230 | - |
dc.relation.journalcode | J01939 | - |
dc.identifier.url | http://www.scientific.net/KEM.342-343.145 | - |
dc.contributor.alternativeName | Lee, Jin Woo | - |
dc.contributor.affiliatedAuthor | Lee, Jin Woo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 342~343 | - |
dc.citation.startPage | 145 | - |
dc.citation.endPage | 148 | - |
dc.identifier.bibliographicCitation | Key Engineering Materials, Vol.342~343 : 145-148, 2007 | - |
dc.identifier.rimsid | 36458 | - |
dc.type.rims | ART | - |
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