Cited 23 times in
Changes in Serum and Ascitic Monocyte Chemotactic Protein-1 (MCP-1) and IL-10 Levels in Cirrhotic Patients with Spontaneous Bacterial Peritonitis
DC Field | Value | Language |
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dc.contributor.author | 김윤재 | - |
dc.contributor.author | 김자경 | - |
dc.contributor.author | 김재학 | - |
dc.contributor.author | 방승민 | - |
dc.contributor.author | 안상훈 | - |
dc.contributor.author | 전재윤 | - |
dc.contributor.author | 조재희 | - |
dc.contributor.author | 한광협 | - |
dc.date.accessioned | 2014-12-21T16:47:16Z | - |
dc.date.available | 2014-12-21T16:47:16Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1079-9907 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/96350 | - |
dc.description.abstract | Spontaneous bacterial peritonitis (SBP) is a prototypical infectious disease of cirrhotic patients. It has been suggested that cirrhotic patients' response to infection is less effective because of differences in the inflammatory and immune reactions. This study aimed to investigate the expression of the inflammatory cytokines monocyte chemotactic protein-1 (MCP-1) and interleukin-10 (IL-10) in cirrhotic patients with SBP. The MCP1 and IL-10 levels in the sera and ascitic fluids of cirrhotic patients with (n = 40) or without SBP (n=17) were serially analyzed by ELISA. In the non-SBP group, the mean MCP-1 levels in sera and ascites were 53.0 +/- 45.8 pg/mL and 197.5 +/- 109.5 pg/mL, respectively, and the IL-10 levels were 10.9 +/- 9.5 pg/mL and 77.6 +/- 79.7 pg/mL, respectively. In the SBP group, the mean MCP-1 levels in serum and ascites before treatment were 164.7 +/- 126.4 pg/mL and 365.3 +/- 583.0 pg/mL, respectively, and the IL-10 levels were 31.4 +/- 44.1 pg/mL and 188.1 +/- 189.5 pg/mL, respectively. The sera MCP-1 and ascites IL-10 levels differed significantly between the two groups. In the SBP group, sera and ascitic MCP-1 and IL-10 levels fell during treatment. The low MCP-1 and IL-10 levels on the seventh day of treatment were found to have a statistically significant relationship to patient survival. MCP-1 and IL-10 levels in sera and ascites may be related to the clinical course of SBP. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 227~230 | - |
dc.relation.isPartOf | JOURNAL OF INTERFERON AND CYTOKINE RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Changes in Serum and Ascitic Monocyte Chemotactic Protein-1 (MCP-1) and IL-10 Levels in Cirrhotic Patients with Spontaneous Bacterial Peritonitis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Ja Kyung Kim | - |
dc.contributor.googleauthor | Chae Yoon Chon | - |
dc.contributor.googleauthor | Young Myoung Moon | - |
dc.contributor.googleauthor | Kwang-Hyub Han | - |
dc.contributor.googleauthor | Sang Hoon Ahn | - |
dc.contributor.googleauthor | Seung Min Bang | - |
dc.contributor.googleauthor | Jae Hee Cho | - |
dc.contributor.googleauthor | Yoon Jae Kim | - |
dc.contributor.googleauthor | Jae Hak Kim | - |
dc.identifier.doi | 10.1089/jir.2006.0055 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00792 | - |
dc.contributor.localId | A00852 | - |
dc.contributor.localId | A00871 | - |
dc.contributor.localId | A01786 | - |
dc.contributor.localId | A02226 | - |
dc.contributor.localId | A03902 | - |
dc.contributor.localId | A04268 | - |
dc.contributor.localId | A03544 | - |
dc.relation.journalcode | J01460 | - |
dc.identifier.eissn | 1557-7465 | - |
dc.identifier.url | http://online.liebertpub.com/doi/abs/10.1089/jir.2006.0055 | - |
dc.contributor.alternativeName | Kim, Yoon Jae | - |
dc.contributor.alternativeName | Kim, Ja Kyung | - |
dc.contributor.alternativeName | Kim, Jae Hak | - |
dc.contributor.alternativeName | Bang, Seung Min | - |
dc.contributor.alternativeName | Ahn, Sang Hoon | - |
dc.contributor.alternativeName | Chon, Chae Yoon | - |
dc.contributor.alternativeName | Cho, Jae Hee | - |
dc.contributor.alternativeName | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Kim, Yoon Jae | - |
dc.contributor.affiliatedAuthor | Kim, Ja Kyung | - |
dc.contributor.affiliatedAuthor | Kim, Jae Hak | - |
dc.contributor.affiliatedAuthor | Bang, Seung Min | - |
dc.contributor.affiliatedAuthor | Ahn, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Cho, Jae Hee | - |
dc.contributor.affiliatedAuthor | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Chon, Chae Yoon | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 27 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 227 | - |
dc.citation.endPage | 230 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, Vol.27(3) : 227-230, 2007 | - |
dc.identifier.rimsid | 37030 | - |
dc.type.rims | ART | - |
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