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Blood Pulsation의 효과가 뇌 활성화에 미치는 영향을 알아보는 방법

Other Titles
 Estimation Method for Brain Activities are Influenced by Blood Pulsation Effect 
 이원호  ;  구정훈  ;  김선일  ;  김인영  ;  윤강준  ;  김재진  ;  박진식  ;  한기완  ;  이형래 
 Journal of Biomedical Engineering Research (의공학회지), Vol.28(3) : 338-343, 2007 
Journal Title
 Journal of Biomedical Engineering Research (의공학회지) 
Issue Date
BOLD T2*-weighted MR images reflects cortical blood flow and oxygenation alterations. fMRI study relies on the detection of localized changes in BOLD signal intensity. Since fMRI measures the very small modulations in BOLD signal intensity that occur during changes in brain activity, it is also very sensitive to small signal intensity variations caused by physiologic noise during the scan. Due to the complexity of movement of various organs associated with heart beat, it is important to reduce cardiac related noise rather than other physiological noise which could be required with relatively simple method. Therefore, a number of methods have been developed for the estimation and reduction of cardiac noise in fMRI study. But, each method has limitation. In this study, we proposed a new estimation method for brain activities influenced by blood pulsation effect using regression analysis with blood pulsation signal and the correspond slice of fMRI. We could find out that the right anterior cingulate cortex and right olfactory cortex and left olfactory cortex were largely influenced by blood pulsation effect for new method. These observed areas are mostly on the structure of anterior cerebral artery in the brain. That is convinced with that our method would be valid and our new method is easier to apply in practice and reduce computational burden than the retrospective method.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Jin(김재진) ORCID logo https://orcid.org/0000-0002-1395-4562
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