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Haplotypes and mutation analysis of 22 Y-chromosomal STRs in Korean father-son pairs

DC Field Value Language
dc.contributor.author박명진-
dc.contributor.author신경진-
dc.contributor.author양우익-
dc.contributor.author이환영-
dc.contributor.author정욱희-
dc.contributor.author조상호-
dc.date.accessioned2014-12-21T16:41:33Z-
dc.date.available2014-12-21T16:41:33Z-
dc.date.issued2007-
dc.identifier.issn0937-9827-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/96169-
dc.description.abstractWe analyzed 369 Korean father/son haplotype transfers in 355 families at 22 Y-STRs (DYS19, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS388, DYS437, DYS438, DYS439, DYS446, DYS447, DYS448, DYS449, DYS456, DYS458, DYS464, DYS635, and GATA H4.1). A total of 350 haplotypes were observed with an overall haplotype diversity of 0.9999. Among these, 345 were unique and five were found twice. Furthermore, 36 mutations were identified, giving locus-specific mutation rate estimates between 0.0 and 19.0 × 10−3 per generation and an average mutation rate estimate of 3.9 × 10−3 (95% CI 2.7–5.4 × 10−3). The compilation of Y-STR mutation events for the present study and previous studies demonstrates that DYS449, DYS458, DYS635, DYS456 and DYS439 are the most prone to mutations and that their overall average mutation rate estimate is 2.36 × 10–3 (95% CI 2.03–2.73 × 10–33).-
dc.description.statementOfResponsibilityopen-
dc.format.extent128~135-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF LEGAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAsian Continental Ancestry Group/genetics*-
dc.subject.MESHChromosomes, Human, Y/genetics*-
dc.subject.MESHDNA Mutational Analysis-
dc.subject.MESHFathers-
dc.subject.MESHGenetic Variation-
dc.subject.MESHHaplotypes/genetics*-
dc.subject.MESHHumans-
dc.subject.MESHKorea-
dc.subject.MESHMale-
dc.subject.MESHMicrosatellite Repeats/genetics*-
dc.subject.MESHMutation/genetics*-
dc.subject.MESHPaternity*-
dc.subject.MESHPolymorphism, Single Nucleotide-
dc.subject.MESHReproducibility of Results-
dc.titleHaplotypes and mutation analysis of 22 Y-chromosomal STRs in Korean father-son pairs-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Forensic Medicine (법의학)-
dc.contributor.googleauthorHwan Young Lee-
dc.contributor.googleauthorMyung Jin Park-
dc.contributor.googleauthorKyoung-Jin Shin-
dc.contributor.googleauthorSang-Ho Cho-
dc.contributor.googleauthorWoo Ick Yang-
dc.contributor.googleauthorHan Young Lee-
dc.contributor.googleauthorUkhee Chung-
dc.identifier.doi10.1007/s00414-006-0130-x-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01456-
dc.contributor.localIdA02085-
dc.contributor.localIdA02300-
dc.contributor.localIdA03335-
dc.contributor.localIdA03673-
dc.contributor.localIdA03825-
dc.relation.journalcodeJ01126-
dc.identifier.eissn1437-1596-
dc.identifier.pmid17106736-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00414-006-0130-x-
dc.subject.keywordY chromosome STR-
dc.subject.keywordHaplotypes-
dc.subject.keywordMutation rate-
dc.subject.keywordKoreans-
dc.contributor.alternativeNamePark, Myung Jin-
dc.contributor.alternativeNameShin, Kyoung Jin-
dc.contributor.alternativeNameYang, Woo Ick-
dc.contributor.alternativeNameLee, Hwan Young-
dc.contributor.alternativeNameChung, Uk Hee-
dc.contributor.alternativeNameCho, Sang Ho-
dc.contributor.affiliatedAuthorPark, Myung Jin-
dc.contributor.affiliatedAuthorShin, Kyoung Jin-
dc.contributor.affiliatedAuthorYang, Woo Ick-
dc.contributor.affiliatedAuthorLee, Hwan Young-
dc.contributor.affiliatedAuthorChung, Uk Hee-
dc.contributor.affiliatedAuthorCho, Sang Ho-
dc.rights.accessRightsnot free-
dc.citation.volume121-
dc.citation.number2-
dc.citation.startPage128-
dc.citation.endPage135-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF LEGAL MEDICINE, Vol.121(2) : 128-135, 2007-
dc.identifier.rimsid34953-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Forensic Medicine (법의학과) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers

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