Cited 88 times in
Use of a Modified Atkins Diet in Intractable Childhood Epilepsy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김흥동 | - |
dc.date.accessioned | 2014-12-21T16:35:24Z | - |
dc.date.available | 2014-12-21T16:35:24Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0013-9580 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95972 | - |
dc.description.abstract | PURPOSE: To evaluate the efficacy, safety and tolerability of a modified Atkins diet in intractable childhood epilepsy. METHODS: Fourteen children with epilepsy were treated prospectively with a modified Atkins diet. Outcome measures included seizure frequency, adverse reactions and tolerability to the diet; blood beta-hydroxybutyrate and urine ketones were also measured. RESULTS: Six months after diet initiation, seven (50%) remained on the diet, five (36%) had >50% seizure reduction, and three (21%) were seizure free. The diet was well tolerated by 12 (86%) patients. Most complications were transient and were successfully managed by careful follow-up and conservative strategies. A consistently strong ketosis (beta-hydroxybutyrate of >3 mmol/L) seemed to be important for maintaining the efficacy of the diet therapy. CONCLUSIONS: The modified Atkins diet was well tolerated and sometimes a modified Atkins diet can be substituted for the conventional ketogenic diet. Serious complications were rare, but long-term complications remain to be determined. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 182~186 | - |
dc.relation.isPartOf | EPILEPSIA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | 3-Hydroxybutyric Acid/blood | - |
dc.subject.MESH | 3-Hydroxybutyric Acid/metabolism | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Diet, Carbohydrate-Restricted/adverse effects | - |
dc.subject.MESH | Diet, Carbohydrate-Restricted/methods* | - |
dc.subject.MESH | Dietary Proteins/administration & dosage | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Epilepsy/diet therapy* | - |
dc.subject.MESH | Epilepsy/metabolism | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Ketones/urine | - |
dc.subject.MESH | Ketosis/metabolism | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Use of a Modified Atkins Diet in Intractable Childhood Epilepsy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Hoon-Chul Kang | - |
dc.contributor.googleauthor | Hyun Sug Lee | - |
dc.contributor.googleauthor | Heung Dong Kim | - |
dc.contributor.googleauthor | Tae-Sung Ko | - |
dc.contributor.googleauthor | Du Cheol Kang | - |
dc.contributor.googleauthor | Su Jeong You | - |
dc.identifier.doi | 10.1111/j.1528-1167.2006.00910.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01208 | - |
dc.relation.journalcode | J00793 | - |
dc.identifier.eissn | 1528-1167 | - |
dc.identifier.pmid | 17241226 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1528-1167.2006.00910.x/abstract | - |
dc.contributor.alternativeName | Kim, Heung Dong | - |
dc.contributor.affiliatedAuthor | Kim, Heung Dong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 48 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 182 | - |
dc.citation.endPage | 186 | - |
dc.identifier.bibliographicCitation | EPILEPSIA, Vol.48(1) : 182-186, 2007 | - |
dc.identifier.rimsid | 35344 | - |
dc.type.rims | ART | - |
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