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Catastrophic antiphospholipid syndrome in a 7-year-old girl

Authors
 Jee Min Park  ;  Jae Il Shin  ;  Do Yun Lee  ;  Seung Koo Lee  ;  Myung Joon Kim  ;  Jae Seung Lee  ;  Dong Soo Kim  ;  Youn Ho Shin 
Citation
 CLINICAL RHEUMATOLOGY, Vol.26(6) : 1011-1013, 2007 
Journal Title
CLINICAL RHEUMATOLOGY
ISSN
 0770-3198 
Issue Date
2007
Abstract
Antiphospholipid syndrome (APS) has been recognized as the leading cause of vascular thrombosis in children. The syndrome may occur in isolation or in association with an underlying systemic disease, particularly systemic lupus erythematosus. Less than 1% of patients with APS present with a life-threatening condition resulting from thrombosis in multiple organs and subsequent multiorgan failure, which is defined as catastrophic APS. Early recognition of APS is essential because prompt and appropriate management can result in favorable outcome. We present the case of a 7-year-old girl with APS who presented with cerebral, femoral, and renal involvement in the second week of the disease progress. The patient presented with multiple thrombotic episodes and rapidly progressive renal failure. Renal cortical infarction was diagnosed by magnetic resonance imaging.
Full Text
http://link.springer.com/article/10.1007%2Fs10067-006-0251-0
DOI
10.1007/s10067-006-0251-0
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Soo(김동수)
Kim, Myung Joon(김명준) ORCID logo https://orcid.org/0000-0002-4608-0275
Park, Jee Min(박지민)
Shin, Youn Ho(신윤호)
Shin, Jae Il(신재일) ORCID logo https://orcid.org/0000-0003-2326-1820
Lee, Do Yun(이도연)
Lee, Seung Koo(이승구) ORCID logo https://orcid.org/0000-0001-5646-4072
Lee, Jae Seung(이재승)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/95909
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