Cited 17 times in
The adaptation and relationship of FGF-23 to changes in mineral metabolism in Graves' disease
DC Field | Value | Language |
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dc.contributor.author | 강은석 | - |
dc.contributor.author | 김경래 | - |
dc.contributor.author | 김세화 | - |
dc.contributor.author | 박세은 | - |
dc.contributor.author | 안철우 | - |
dc.contributor.author | 이유미 | - |
dc.contributor.author | 이은직 | - |
dc.contributor.author | 이현철 | - |
dc.contributor.author | 임승길 | - |
dc.contributor.author | 조미애 | - |
dc.contributor.author | 차봉수 | - |
dc.contributor.author | Kang, Eun Seok | - |
dc.contributor.author | Kim, Kyung Rae | - |
dc.contributor.author | Park, Se Eun | - |
dc.contributor.author | Ahn, Chul Woo | - |
dc.contributor.author | Rhee, Yumie | - |
dc.contributor.author | Lee, Eun Jig | - |
dc.contributor.author | Lee, Hyun Chul | - |
dc.contributor.author | Lim, Sung Kil | - |
dc.contributor.author | Cho, Mi Ae | - |
dc.contributor.author | Cha, Bong Soo | - |
dc.contributor.author | Kim, Se Hwa | - |
dc.date.accessioned | 2014-12-21T16:32:31Z | - |
dc.date.available | 2014-12-21T16:32:31Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0300-0664 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95884 | - |
dc.description.abstract | OBJECTIVE: The aim of this study was to observe the changes in bone and mineral metabolism and to confirm the regulation of fibroblast growth factor-23 (FGF-23) in untreated Graves' disease. PATIENTS AND MEASUREMENTS: The study comprised 39 patients, with or without Graves' disease. The Graves' disease group was made up of 21 newly diagnosed patients, enrolled before starting treatment. Their disease was determined by biochemical and radiological means. The control group was composed of 18 people who were proven to be euthyroid without any diseases affecting bone and mineral metabolism. FGF-23, calcium, phosphate, PTH, 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)2D] levels and bone turnover markers were compared between these groups. RESULTS: Serum calcium and phosphate, plasma FGF-23 and free T4 were significantly higher in the Graves' disease group than in the healthy control group (P < 0.05). The bone turnover markers serum osteocalcin and C-terminal cross-linked telopeptide of type 1 collagen (s-CTx) were also significantly elevated in the Graves' disease group, and had a positive correlation with free T4 levels. However, there was no significant decrease in PTH and 1,25(OH)2D in the Graves' disease group. Plasma levels of FGF-23 exhibited a positive correlation with serum phosphate levels and with free T4 levels (P < 0.05). CONCLUSIONS: These findings suggest that FGF-23 is physiologically related to serum phosphate homeostasis, as indicated indirectly by the changes in bone and mineral metabolism, in untreated Graves' disease. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | CLINICAL ENDOCRINOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | The adaptation and relationship of FGF-23 to changes in mineral metabolism in Graves' disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Se Eun Park | - |
dc.contributor.googleauthor | Mi Ae Cho | - |
dc.contributor.googleauthor | Sung-Kil Lim | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.contributor.googleauthor | Kyung Rae Kim | - |
dc.contributor.googleauthor | Eun Jig Lee | - |
dc.contributor.googleauthor | Bong Soo Cha | - |
dc.contributor.googleauthor | Chul Woo Ahn | - |
dc.contributor.googleauthor | Eun Seok Kang | - |
dc.contributor.googleauthor | Yumie Rhee | - |
dc.contributor.googleauthor | Se Hwa Kim | - |
dc.identifier.doi | 10.1111/j.1365-2265.2007.02824.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00068 | - |
dc.contributor.localId | A00294 | - |
dc.contributor.localId | A01521 | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A03012 | - |
dc.contributor.localId | A03050 | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A03375 | - |
dc.contributor.localId | A03816 | - |
dc.contributor.localId | A03996 | - |
dc.contributor.localId | A00609 | - |
dc.relation.journalcode | J00571 | - |
dc.identifier.eissn | 1365-2265 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2007.02824.x/abstract | - |
dc.contributor.alternativeName | Kang, Eun Seok | - |
dc.contributor.alternativeName | Kim, Kyung Rae | - |
dc.contributor.alternativeName | Kim, Se Hwa | - |
dc.contributor.alternativeName | Park, Se Eun | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Rhee, Yumie | - |
dc.contributor.alternativeName | Lee, Eun Jig | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.alternativeName | Cho, Mi Ae | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kang, Eun Seok | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Rae | - |
dc.contributor.affiliatedAuthor | Park, Se Eun | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Woo | - |
dc.contributor.affiliatedAuthor | Rhee, Yumie | - |
dc.contributor.affiliatedAuthor | Lee, Eun Jig | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Lim, Sung Kil | - |
dc.contributor.affiliatedAuthor | Cho, Mi Ae | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kim, Se Hwa | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 66 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 854 | - |
dc.citation.endPage | 858 | - |
dc.identifier.bibliographicCitation | CLINICAL ENDOCRINOLOGY, Vol.66(6) : 854-858, 2007 | - |
dc.identifier.rimsid | 53267 | - |
dc.type.rims | ART | - |
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