Cited 14 times in
Development of acetylated HDD kit for preparation of 188Re-HDD/lipiodol
DC Field | Value | Language |
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dc.contributor.author | 강원준 | - |
dc.date.accessioned | 2014-12-21T16:24:53Z | - |
dc.date.available | 2014-12-21T16:24:53Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0969-8043 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95648 | - |
dc.description.abstract | A lipiodol solution of 188Re-4-hexadecyl-2,2,9,9-tetramethyl-4,7-diaza-1,10-decanedithiol (188Re-HDD/lipiodol) is in clinical study for liver cancer therapy. However, formulation of it is difficult due to highly active and unstable sulfhydryl groups. We produced new kits using diacetylated HDD (AHDD), in which sulfhydryl groups are protected. We found that AHDD kit can replace HDD kit due to an increased stability for formulation, the better radiolabeling efficiency (78%) and the equivalent biodistribution pattern in mice. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 64~69 | - |
dc.relation.isPartOf | APPLIED RADIATION AND ISOTOPES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Development of acetylated HDD kit for preparation of 188Re-HDD/lipiodol | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Nuclear Medicine (핵의학) | - |
dc.contributor.googleauthor | Yun-Sang Lee | - |
dc.contributor.googleauthor | Jae Min Jeong | - |
dc.contributor.googleauthor | Young-Ger Suh | - |
dc.contributor.googleauthor | Myung Chul Lee | - |
dc.contributor.googleauthor | June-Key Chung | - |
dc.contributor.googleauthor | Dong Soo Lee | - |
dc.contributor.googleauthor | Won Jun Kang | - |
dc.contributor.googleauthor | Heung Sik Yoon | - |
dc.contributor.googleauthor | Jung Woo Lee | - |
dc.contributor.googleauthor | Miwon Son | - |
dc.contributor.googleauthor | Hak Jeong Lee | - |
dc.contributor.googleauthor | Young Soo Chang | - |
dc.contributor.googleauthor | Young Joo Kim | - |
dc.identifier.doi | 10.1016/j.apradiso.2006.07.008 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00062 | - |
dc.relation.journalcode | J00206 | - |
dc.identifier.eissn | 1872-9800 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S096980430600296X | - |
dc.contributor.alternativeName | Kang, Won Jun | - |
dc.contributor.affiliatedAuthor | Kang, Won Jun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 65 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 64 | - |
dc.citation.endPage | 69 | - |
dc.identifier.bibliographicCitation | APPLIED RADIATION AND ISOTOPES, Vol.65(1) : 64-69, 2007 | - |
dc.identifier.rimsid | 44989 | - |
dc.type.rims | ART | - |
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