Cited 72 times in
Prognostic significance of circumferential resection margin following total mesorectal excision and adjuvant chemoradiotherapy in patients with rectal cancer
DC Field | Value | Language |
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dc.contributor.author | 김남규 | - |
dc.contributor.author | 김호근 | - |
dc.contributor.author | 백승혁 | - |
dc.contributor.author | 손승국 | - |
dc.contributor.author | 이강영 | - |
dc.contributor.author | 이영찬 | - |
dc.contributor.author | 조장환 | - |
dc.date.accessioned | 2014-12-21T16:24:00Z | - |
dc.date.available | 2014-12-21T16:24:00Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95620 | - |
dc.description.abstract | BACKGROUND: This study was designed to evaluate the prognostic value of circumferential resection margin (CRM) in rectal cancer patients who underwent curative resection with adjuvant chemoradiotherapy (CRT). METHODS: We studied 504 patients who underwent total mesorectal excision with adjuvant CRT for rectal cancer between 1997 and 2001. The patients were divided into two groups: a negative CRM group (CRM > 1 mm) and a positive CRM group (CRM <or= 1 mm). The survival rates, local recurrence rates, and systemic recurrence rates were compared between groups. RESULTS: The negative CRM group had 460 patients and the positive CRM group had 44 patients. The 5-year local and systemic recurrence rates were 11.3 and 25.3%, respectively, in the negative CRM group and 35.2 and 60.8% in the positive CRM group, respectively. The cancer-specific 5-year survival rates for the two groups were 72.5 and 26.9% (P < .001), respectively. CRM was found to be an independent prognostic factor by multivariate analyses which were adjusted for known outcome predictors (P < .001). CONCLUSION: Oncological outcome for patients in the positive CRM group is less favorable than for those in the negative CRM group. Adjuvant CRT is not a definite treatment modality that can be used to compensate for a positive CRM following TME and adjuvant CRT in patients with TNM stage II or III rectal cancer. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 462~469 | - |
dc.relation.isPartOf | ANNALS OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Prognostic significance of circumferential resection margin following total mesorectal excision and adjuvant chemoradiotherapy in patients with rectal cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Seung Hyuk Baik | - |
dc.contributor.googleauthor | Nam Kyu Kim | - |
dc.contributor.googleauthor | Chang Hwan Cho | - |
dc.contributor.googleauthor | Seung Kook Sohn | - |
dc.contributor.googleauthor | Kang Young Lee | - |
dc.contributor.googleauthor | Hoguen Kim | - |
dc.contributor.googleauthor | Young Chan Lee | - |
dc.identifier.doi | 10.1245/s10434-006-9171-0 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00353 | - |
dc.contributor.localId | A01183 | - |
dc.contributor.localId | A01827 | - |
dc.contributor.localId | A01978 | - |
dc.contributor.localId | A02640 | - |
dc.contributor.localId | A02965 | - |
dc.contributor.localId | A03894 | - |
dc.relation.journalcode | J00179 | - |
dc.identifier.eissn | 1534-4681 | - |
dc.identifier.url | http://link.springer.com/article/10.1245%2Fs10434-006-9171-0 | - |
dc.contributor.alternativeName | Kim, Nam Kyu | - |
dc.contributor.alternativeName | Kim, Ho Keun | - |
dc.contributor.alternativeName | Baik, Seung Hyuk | - |
dc.contributor.alternativeName | Sohn, Seung Kook | - |
dc.contributor.alternativeName | Lee, Kang Young | - |
dc.contributor.alternativeName | Lee, Young Chan | - |
dc.contributor.alternativeName | Cho, Chang Hwan | - |
dc.contributor.affiliatedAuthor | Kim, Nam Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Ho Keun | - |
dc.contributor.affiliatedAuthor | Baik, Seung Hyuk | - |
dc.contributor.affiliatedAuthor | Sohn, Seung Kook | - |
dc.contributor.affiliatedAuthor | Lee, Kang Young | - |
dc.contributor.affiliatedAuthor | Lee, Young Chan | - |
dc.contributor.affiliatedAuthor | Cho, Chang Hwan | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 14 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 462 | - |
dc.citation.endPage | 469 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL ONCOLOGY, Vol.14(2) : 462-469, 2007 | - |
dc.identifier.rimsid | 44971 | - |
dc.type.rims | ART | - |
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