147 354

Cited 8 times in

The impact of local and regional recurrence on distant metastasis and survival in patients treated with breast conservation therapy

DC FieldValueLanguage
dc.contributor.author김승일-
dc.contributor.author박병우-
dc.contributor.author박세호-
dc.contributor.author박형석-
dc.contributor.author이종석-
dc.contributor.author이준상-
dc.date.accessioned2014-12-20T17:53:00Z-
dc.date.available2014-12-20T17:53:00Z-
dc.date.issued2011-
dc.identifier.issn1738-6756-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/95436-
dc.description.abstractPURPOSE: We evaluated the effect of local recurrence (LR) and regional recurrence (RR) on distant metastasis and survival in patients treated with breast conservation therapy (BCT). METHODS: We analyzed 907 patients who were treated for invasive breast cancer between 1993 and 2006. With 53 months of follow-up, 28 patients (3.1%) developed LR in the breast and 12 patients (1.3%) developed RR before distant metastasis. LR and RR were separated into four patterns to determine the prognostic relevance of recurrence site and time to recurrence: LR within 3 years (early LR), LR after 3 years (late LR), RR within 3 years (early RR), and RR after 3 years (late RR). RESULTS: Early LR (hazard ratio [HR], 4.76; p=0.003) and early RR (HR, 18.16; p<0.001) were independent predictors of distant metastasis. In terms of overall survival, early LR (HR, 5.24; p=0.002), and early RR (HR, 18.80; p<0.001) were significantly related with poor survival. Patients with late LR/RR had a similar favorable prognosis compared with patients who never experienced LR/RR. CONCLUSION: The result suggests that time to LR/RR following BCT is a significant predictor developing a distant metastasis and surviving.-
dc.description.statementOfResponsibilityopen-
dc.format.extent191~197-
dc.relation.isPartOfJOURNAL OF BREAST CANCER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleThe impact of local and regional recurrence on distant metastasis and survival in patients treated with breast conservation therapy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorJong Seok Lee-
dc.contributor.googleauthorSeung Il Kim-
dc.contributor.googleauthorHyung Seok Park-
dc.contributor.googleauthorJun Sang Lee-
dc.contributor.googleauthorSeho Park-
dc.contributor.googleauthorByeong-Woo Park-
dc.identifier.doi10.4048/jbc.2011.14.3.191-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03143-
dc.contributor.localIdA00658-
dc.contributor.localIdA01475-
dc.contributor.localIdA01524-
dc.contributor.localIdA01753-
dc.contributor.localIdA03175-
dc.relation.journalcodeJ01279-
dc.identifier.eissn2092-9900-
dc.identifier.pmid22031800-
dc.subject.keywordBreast conservation therapy-
dc.subject.keywordDistant metastasis-
dc.subject.keywordLocal recurrence-
dc.subject.keywordRegional recurrence-
dc.subject.keywordSurvival-
dc.contributor.alternativeNameKim, Seung Il-
dc.contributor.alternativeNamePark, Byeong Woo-
dc.contributor.alternativeNamePark, Se Ho-
dc.contributor.alternativeNamePark, Hyung Seok-
dc.contributor.alternativeNameLee, Jong Seok-
dc.contributor.alternativeNameLee, Jun Sang-
dc.contributor.affiliatedAuthorLee, Jong Seok-
dc.contributor.affiliatedAuthorKim, Seung Il-
dc.contributor.affiliatedAuthorPark, Byeong Woo-
dc.contributor.affiliatedAuthorPark, Se Ho-
dc.contributor.affiliatedAuthorPark, Hyung Seok-
dc.contributor.affiliatedAuthorLee, Jun Sang-
dc.rights.accessRightsfree-
dc.citation.volume14-
dc.citation.number3-
dc.citation.startPage191-
dc.citation.endPage197-
dc.identifier.bibliographicCitationJOURNAL OF BREAST CANCER, Vol.14(3) : 191-197, 2011-
dc.identifier.rimsid40817-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.