Cited 13 times in
The impact of local and regional recurrence on distant metastasis and survival in patients treated with breast conservation therapy
DC Field | Value | Language |
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dc.contributor.author | 김승일 | - |
dc.contributor.author | 박병우 | - |
dc.contributor.author | 박세호 | - |
dc.contributor.author | 박형석 | - |
dc.contributor.author | 이종석 | - |
dc.contributor.author | 이준상 | - |
dc.date.accessioned | 2014-12-20T17:53:00Z | - |
dc.date.available | 2014-12-20T17:53:00Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1738-6756 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95436 | - |
dc.description.abstract | PURPOSE: We evaluated the effect of local recurrence (LR) and regional recurrence (RR) on distant metastasis and survival in patients treated with breast conservation therapy (BCT). METHODS: We analyzed 907 patients who were treated for invasive breast cancer between 1993 and 2006. With 53 months of follow-up, 28 patients (3.1%) developed LR in the breast and 12 patients (1.3%) developed RR before distant metastasis. LR and RR were separated into four patterns to determine the prognostic relevance of recurrence site and time to recurrence: LR within 3 years (early LR), LR after 3 years (late LR), RR within 3 years (early RR), and RR after 3 years (late RR). RESULTS: Early LR (hazard ratio [HR], 4.76; p=0.003) and early RR (HR, 18.16; p<0.001) were independent predictors of distant metastasis. In terms of overall survival, early LR (HR, 5.24; p=0.002), and early RR (HR, 18.80; p<0.001) were significantly related with poor survival. Patients with late LR/RR had a similar favorable prognosis compared with patients who never experienced LR/RR. CONCLUSION: The result suggests that time to LR/RR following BCT is a significant predictor developing a distant metastasis and surviving. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 191~197 | - |
dc.relation.isPartOf | JOURNAL OF BREAST CANCER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | The impact of local and regional recurrence on distant metastasis and survival in patients treated with breast conservation therapy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Jong Seok Lee | - |
dc.contributor.googleauthor | Seung Il Kim | - |
dc.contributor.googleauthor | Hyung Seok Park | - |
dc.contributor.googleauthor | Jun Sang Lee | - |
dc.contributor.googleauthor | Seho Park | - |
dc.contributor.googleauthor | Byeong-Woo Park | - |
dc.identifier.doi | 10.4048/jbc.2011.14.3.191 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03143 | - |
dc.contributor.localId | A00658 | - |
dc.contributor.localId | A01475 | - |
dc.contributor.localId | A01524 | - |
dc.contributor.localId | A01753 | - |
dc.contributor.localId | A03175 | - |
dc.relation.journalcode | J01279 | - |
dc.identifier.eissn | 2092-9900 | - |
dc.identifier.pmid | 22031800 | - |
dc.subject.keyword | Breast conservation therapy | - |
dc.subject.keyword | Distant metastasis | - |
dc.subject.keyword | Local recurrence | - |
dc.subject.keyword | Regional recurrence | - |
dc.subject.keyword | Survival | - |
dc.contributor.alternativeName | Kim, Seung Il | - |
dc.contributor.alternativeName | Park, Byeong Woo | - |
dc.contributor.alternativeName | Park, Se Ho | - |
dc.contributor.alternativeName | Park, Hyung Seok | - |
dc.contributor.alternativeName | Lee, Jong Seok | - |
dc.contributor.alternativeName | Lee, Jun Sang | - |
dc.contributor.affiliatedAuthor | Lee, Jong Seok | - |
dc.contributor.affiliatedAuthor | Kim, Seung Il | - |
dc.contributor.affiliatedAuthor | Park, Byeong Woo | - |
dc.contributor.affiliatedAuthor | Park, Se Ho | - |
dc.contributor.affiliatedAuthor | Park, Hyung Seok | - |
dc.contributor.affiliatedAuthor | Lee, Jun Sang | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 14 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 191 | - |
dc.citation.endPage | 197 | - |
dc.identifier.bibliographicCitation | JOURNAL OF BREAST CANCER, Vol.14(3) : 191-197, 2011 | - |
dc.identifier.rimsid | 40817 | - |
dc.type.rims | ART | - |
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