Cited 9 times in
Identification of antigenic proteins in Trichomonas vaginalis
DC Field | Value | Language |
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dc.contributor.author | 김주리 | - |
dc.contributor.author | 박순정 | - |
dc.contributor.author | 신명헌 | - |
dc.contributor.author | 이혜연 | - |
dc.date.accessioned | 2014-12-20T17:50:39Z | - |
dc.date.available | 2014-12-20T17:50:39Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0023-4001 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95361 | - |
dc.description.abstract | Trichomoniasis is a sexually transmitted disease due to infection with Trichomonas vaginalis, and it can cause serious consequences for women's health. To study the virulence factors of this pathogen, T. vaginalis surface proteins were investigated using polyclonal antibodies specific to the membrane fractions of T. vaginalis. The T. vaginalis expression library was constructed by cloning the cDNA derived from mRNA of T. vaginalis into a phage λ Uni-ZAP XR vector, and then used for immunoscreening with the anti-membrane proteins of T. vaginalis antibodies. The immunoreactive proteins identified included adhesion protein AP65-1, α-actinin, kinesin-associated protein, teneurin, and 2 independent hypothetical proteins. Immunofluorescence assays showed that AP65-1, one of the identified immunogenic clones, is prevalent in the whole body of T. vaginalis. This study led us to identify T. vaginalis proteins which may stimulate immune responses by human cells. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 79~83 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF PARASITOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Antigens, Protozoan/genetics | - |
dc.subject.MESH | Antigens, Protozoan/immunology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Molecular Sequence Data | - |
dc.subject.MESH | Protozoan Proteins/genetics | - |
dc.subject.MESH | Protozoan Proteins/immunology* | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Trichomonas Infections/parasitology | - |
dc.subject.MESH | Trichomonas vaginalis/genetics | - |
dc.subject.MESH | Trichomonas vaginalis/immunology* | - |
dc.title | Identification of antigenic proteins in Trichomonas vaginalis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Environmental Medical Biology (환경의생물학) | - |
dc.contributor.googleauthor | Hye-Yeon Lee | - |
dc.contributor.googleauthor | Sujin Hyung | - |
dc.contributor.googleauthor | Jong Woong Lee | - |
dc.contributor.googleauthor | Juri Kim | - |
dc.contributor.googleauthor | Myeong Heon Shin | - |
dc.contributor.googleauthor | Jae-Sook Ryu | - |
dc.contributor.googleauthor | Soon-Jung Park | - |
dc.identifier.doi | 10.3347/kjp.2011.49.1.79 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00933 | - |
dc.contributor.localId | A01545 | - |
dc.contributor.localId | A02099 | - |
dc.contributor.localId | A03314 | - |
dc.relation.journalcode | J01957 | - |
dc.identifier.eissn | 1738-0006 | - |
dc.identifier.pmid | 21461274 | - |
dc.subject.keyword | Trichomonas vaginalis | - |
dc.subject.keyword | antigenic protein | - |
dc.subject.keyword | membrane protein | - |
dc.subject.keyword | immunoscreening | - |
dc.contributor.alternativeName | Kim, Ju Ri | - |
dc.contributor.alternativeName | Park, Soon Jung | - |
dc.contributor.alternativeName | Shin, Myeong Heon | - |
dc.contributor.alternativeName | Lee, Hye Yeon | - |
dc.contributor.affiliatedAuthor | Kim, Ju Ri | - |
dc.contributor.affiliatedAuthor | Park, Soon Jung | - |
dc.contributor.affiliatedAuthor | Shin, Myeong Heon | - |
dc.contributor.affiliatedAuthor | Lee, Hye Yeon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 49 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 79 | - |
dc.citation.endPage | 83 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF PARASITOLOGY, Vol.49(1) : 79-83, 2011 | - |
dc.identifier.rimsid | 48320 | - |
dc.type.rims | ART | - |
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