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In vitro fertilization and embryo transfer outcomes in relation to myometrial thickness

Authors
 Hyun Sik Youm  ;  Young Sik Choi  ;  Hyuck Dong Han 
Citation
 JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, Vol.28(11) : 1135-1140, 2011 
Journal Title
 JOURNAL OF ASSISTED REPRODUCTION AND GENETICS 
ISSN
 1058-0468 
Issue Date
2011
MeSH
Abortion, Induced/statistics & numerical data ; Adult ; Embryo Transfer ; Endometriosis/diagnostic imaging ; Endometriosis/pathology ; Female ; Fertilization in Vitro* ; Humans ; Myometrium/diagnostic imaging* ; Myometrium/pathology* ; Pregnancy ; Pregnancy Complications ; Pregnancy Outcome/epidemiology ; Pregnancy Rate* ; Retrospective Studies ; Ultrasonography
Keywords
Myometrial thickness ; Adenomyosis ; IVF-ET outcome ; TVUS
Abstract
PURPOSE: To evaluate the effects of myometrial thickening on the outcomes of in vitro fertilization and embryo transfer (IVF-ET). METHODS: Four hundred thirteen patients, a total of 551 IVF-ET cycles, were divided into group A (<2.00 cm), group B (2.00-2.49 cm), and group C (≥2.50 cm) based on myometrial thickness. RESULTS: The implantation, clinical pregnancy, and live birth rates were significantly lower in group C. The abortion rates were significantly higher in group C. Among patients in group B, cases with other sonographic findings suggestive of adenomyosis, such as myometrial striations, heterogeneous myometrium, myometrial cysts, and poor definition of the endometrial-myometrial junction showed lower implantation, clinical pregnancy, live birth rates, and higher abortion rates. CONCLUSIONS: Myometrial thickening of more than 2.50 cm on TVUS exerts overall adverse effects on IVF-ET outcomes. Even with mild thickening (2.00-2.49 cm), the presence of sonographic findings suggestive of adenomyosis is associated with adverse outcomes of IVF-ET.
Files in This Item:
T201194030.pdf Download
DOI
10.1007/s10815-011-9640-7
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Choi, Young Sik(최영식) ORCID logo https://orcid.org/0000-0002-1157-4822
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/95333
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