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Mode of delivery influences the regression of abnormal cervical cytology

 Chung S.M.  ;  Son G.H.  ;  Nam E.J.  ;  Kim Y.H.  ;  Kim Y.T.  ;  Park Y.W.  ;  Kwon J.Y. 
 Gynecologic and Obstetric Investigation, Vol.72(4) : 234-238, 2011 
Journal Title
 Gynecologic and Obstetric Investigation 
Issue Date
Adult ; Cervical Intraepithelial Neoplasia/pathology* ; Cesarean Section ; Delivery, Obstetric/methods* ; Female ; Humans ; Neoplasm Grading ; Neoplasm Regression, Spontaneous/pathology* ; Papanicolaou Test ; Postpartum Period* ; Pregnancy ; Pregnancy Complications, Neoplastic* ; Retrospective Studies ; Uterine Cervical Neoplasms/pathology* ; Vaginal Smears
Delivery mode ; Abnormal cervical cytology ; Regression rate
AIMS: The purpose was to investigate the influence of delivery mode on the postpartum regression of abnormal cervical cytology. METHODS: A retrospective review was conducted of 64 pregnant women with abnormal cervical cytology at Yonsei University Health System in Korea between 2001 and 2008. A Papanicolaou smear and pathological data were categorized into three groups by cervical intraepithelial neoplasia classification. Postpartum evaluation was taken 3-6 months after delivery. The regression rates of cervical cytologic findings were compared between the vaginal delivery group and Cesarean section group. p < 0.05 was considered significant. RESULTS: Of the 64 women, 45 (70.3%) were delivered vaginally and 19 (29.7%) by cesarean section. No significant difference was found between the two groups with respect to age, gestational age, parity, smoking, and HPV (human papilloma virus) screening. Postpartum regression was shown in 39 (92.9%) women who delivered vaginally and in 12 (63.2%) women who underwent cesarean section (p = 0.016). In the cesarean section group, 1 patient had progressed from CIN2 to microinvasive cancer and 2 patients from carcinoma in situ to invasive cancer. CONCLUSION: The rate of spontaneous regression of antepartum abnormal cervical cytology was higher after vaginal delivery
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1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ja Young(권자영) ORCID logo https://orcid.org/0000-0003-3009-6325
Kim, Young Tae(김영태) ORCID logo https://orcid.org/0000-0002-7347-1052
Kim, Young Han(김영한) ORCID logo https://orcid.org/0000-0003-0645-6028
Nam, Eun Ji(남은지)
Park, Yong Won(박용원)
Son, Ga Hyun(손가현)
Chung, Sue Min(정수민)
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