Cited 3 times in
The pleiohomeotic functions as a negative regulator of Drosophila even-skipped gene during embryogenesis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 허만욱 | - |
dc.contributor.author | 전부남 | - |
dc.contributor.author | 최원일 | - |
dc.date.accessioned | 2014-12-20T17:46:28Z | - |
dc.date.available | 2014-12-20T17:46:28Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1016-8478 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/95225 | - |
dc.description.abstract | Polycomb group (PcG) proteins maintain the spatial expression patterns of genes that are involved in cell-fate specification along the anterior-posterior (A/P) axis. This repression requires cis-acting silencers, which are called PcG response elements (PREs). One of the PcG proteins, Pleiohomeotic (Pho), which has a zinc finger DNA binding protein, plays a critical role in recruiting other PcG proteins to bind to PREs. In this study, we characterized the effects of a pho mutation on embryonic segmentation. pho maternal mutant embryos showed various segmental defects including pair-rule gene mutant patterns. Our results indicated that engrailed and even-skipped genes were misexpressed in pho mutant embryos, which caused embryonic segment defects. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 549~554 | - |
dc.relation.isPartOf | MOLECULES AND CELLS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Blastoderm/metabolism | - |
dc.subject.MESH | Cells, Cultured | - |
dc.subject.MESH | DNA-Binding Proteins/genetics | - |
dc.subject.MESH | DNA-Binding Proteins/metabolism | - |
dc.subject.MESH | DNA-Binding Proteins/physiology* | - |
dc.subject.MESH | Drosophila Proteins/genetics* | - |
dc.subject.MESH | Drosophila Proteins/metabolism | - |
dc.subject.MESH | Drosophila Proteins/physiology* | - |
dc.subject.MESH | Drosophila melanogaster/embryology | - |
dc.subject.MESH | Drosophila melanogaster/genetics* | - |
dc.subject.MESH | Embryonic Development/genetics* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gene Expression Regulation, Developmental | - |
dc.subject.MESH | Homeodomain Proteins/genetics* | - |
dc.subject.MESH | Homeodomain Proteins/metabolism | - |
dc.subject.MESH | Larva/anatomy & histology | - |
dc.subject.MESH | Larva/metabolism | - |
dc.subject.MESH | Mutation | - |
dc.subject.MESH | Polycomb-Group Proteins | - |
dc.subject.MESH | Promoter Regions, Genetic | - |
dc.subject.MESH | Protein Binding | - |
dc.subject.MESH | Transcription Factors/genetics* | - |
dc.subject.MESH | Transcription Factors/metabolism | - |
dc.subject.MESH | Transcription Factors/physiology* | - |
dc.title | The pleiohomeotic functions as a negative regulator of Drosophila even-skipped gene during embryogenesis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Life Science (의생명과학부) | - |
dc.contributor.googleauthor | Su Na Kim | - |
dc.contributor.googleauthor | Hyun Pyo Shim | - |
dc.contributor.googleauthor | Bu-Nam Jeon | - |
dc.contributor.googleauthor | Won-Il Choi | - |
dc.contributor.googleauthor | Man-Wook Hur | - |
dc.contributor.googleauthor | Jack R. Girton | - |
dc.contributor.googleauthor | Sang Hee Kim | - |
dc.contributor.googleauthor | Sang-Hak Jeon | - |
dc.identifier.doi | 10.1007/s10059-011-0173-9 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04350 | - |
dc.contributor.localId | A03517 | - |
dc.contributor.localId | A04126 | - |
dc.relation.journalcode | J02273 | - |
dc.identifier.eissn | 0219-1032 | - |
dc.identifier.pmid | 22080372 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs10059-011-0173-9 | - |
dc.subject.keyword | eve | - |
dc.subject.keyword | Drosophila melanogaster | - |
dc.subject.keyword | GAGA | - |
dc.subject.keyword | pleiohomeotic | - |
dc.subject.keyword | Polycomb group genes | - |
dc.subject.keyword | PRE | - |
dc.subject.keyword | segmentation genes | - |
dc.contributor.alternativeName | Hur, Man Wook | - |
dc.contributor.alternativeName | Jeon, Bu Nam | - |
dc.contributor.alternativeName | Choi, Won Il | - |
dc.contributor.affiliatedAuthor | Hur, Man Wook | - |
dc.contributor.affiliatedAuthor | Jeon, Bu Nam | - |
dc.contributor.affiliatedAuthor | Choi, Won Il | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 32 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 549 | - |
dc.citation.endPage | 554 | - |
dc.identifier.bibliographicCitation | MOLECULES AND CELLS, Vol.32(6) : 549-554, 2011 | - |
dc.identifier.rimsid | 28189 | - |
dc.type.rims | ART | - |
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