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Treatment of periorbital wrinkles with 1550- and 1565-nm Er:glass fractional photothermolysis lasers: a simultaneous split-face trial.

Authors
 J.Y. Jung  ;  S.B. Cho  ;  H.J. Chung  ;  J.-U. Shin  ;  K.H. Lee  ;  K.Y. Chung 
Citation
 JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, Vol.25(7) : 811-818, 2011 
Journal Title
 JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 
ISSN
 0926-9959 
Issue Date
2011
MeSH
Adult ; Aged ; Erbium* ; Female ; Humans ; Lasers* ; Middle Aged ; Orbit* ; Skin Aging/radiation effects*
Keywords
1550-nm Er:glass laser ; 1565-nm Er:glass laser ; fractional photothermolysis ; periorbital wrinkles
Abstract
OBJECTIVE: This study aimed to compare the clinical efficacies of 1550- and 1565-nm Er:glass lasers in the treatment of periorbital wrinkles and to evaluate histological changes after treatment. METHODS: Twenty patients received five treatments each at 3-week intervals. The right periorbital area was exposed to the 1550-nm Er:glass laser and the left periorbital area was exposed to the 1565-nm Er:glass laser. Clinical improvement was evaluated by two blinded physicians who assessed comparative photographs using a four-point scale at baseline and 3 months after the final treatments. Skin biopsies were performed in five volunteers before treatment and at 3 months after the final treatment. RESULTS: The mean improvement scores 3 months after treatment with the 1550- and 1565-nm Er:glass lasers were 2.25±0.62 and 2.28±0.59 respectively. Histological examination revealed increased epidermal thickening and decreased solar elastosis 3 months after the final laser treatments. CONCLUSIONS: Both 1550- and 1565-nm Er:glass lasers are safe and effective modalities in the treatment of periorbital wrinkles with no significant differences between the two lasers.
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/j.1468-3083.2010.03870.x/abstract
DOI
10.1111/j.1468-3083.2010.03870.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jung U(신정우) ORCID logo https://orcid.org/0000-0001-5259-6879
Lee, Kwang Hoon(이광훈)
Chung, Kee Yang(정기양) ORCID logo https://orcid.org/0000-0003-3257-0297
Cho, Sung Bin(조성빈)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/95222
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