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항합성효소증후군과 류마티스 관절염의 중첩증후군 1예

Other Titles
 Overlap Syndrome of Antisynthetase Syndrome and Rheumatoid Arthritis: A Case Report 
 장희원  ;  하유정  ;  이수곤  ;  박용범  ;  이광훈  ;  강 윤 
 Korean Journal of Medicine, Vol.81(5) : 673-679, 2011 
Journal Title
 Korean Journal of Medicine 
Issue Date
The antisynthetase syndrome is characterized by anti-Jo-1 antibody production, interstitial lung disease, inflammatory muscle disease, and, in many cases, fever, polyarthritis, Raynaud’s phenomenon, and mechanic’s hands. Joint signs and symptoms occur in up to 90% of patients with antisynthetase syndrome, occasionally as the initial manifestations. Although visual inspection of the hands shows changes that are highly suggestive of rheumatoid arthritis, notable differences exist. Antisynthetase syndrome is a predominantly nonerosive arthropathy with subluxations of the distal interphalangeal joints. It manifests as overlap syndrome with other connective tissue diseases. However, overlap syndrome of antisynthetase syndrome and rheumatoid arthritis is rare. We treated a 51-year-old male patient with overlap syndrome of antisynthetase syndrome and rheumatoid arthritis, and report the case with a review of the literature
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
강윤(Kang, Yoon) ; 박용범(Park, Yong Beom) ; 이광훈(Lee, Kwang Hoon) ; 이수곤(Lee, Soo Kon) ; 장희원(Jang, Hui Won) ; 하유정(Ha, You Jung)
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