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Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea.

Authors
 Kyungwon Lee  ;  Jong Hwa Yum  ;  Yunsop Chong  ;  Jean-Denis Docquier  ;  Gian Maria Rossolini  ;  Seok Hoon Jeong  ;  Dongeun Yong 
Citation
 Antimicrobial Agents and Chemotherapy, Vol.55(12) : 5930-5932, 2011 
Journal Title
 Antimicrobial Agents and Chemotherapy 
ISSN
 0066-4804 
Issue Date
2011
Abstract
The TEM-107 extended-spectrum β-lactamase detected in a Klebsiella pneumoniae clinical isolate had a Gly238Ser substitution compared to the TEM-43 β-lactamase. The MIC of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. Clavulanic acid reduced the MIC of ceftazidime 64-fold.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94908
DOI
10.1128/AAC.05341-11
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실)
Yonsei Authors
용동은(Yong, Dong Eun) ; 이경원(Lee, Kyung Won) ; 정석훈(Jeong, Seok Hoon) ; 정윤섭(Chong, Yun Sop)
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