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Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea.

Authors
 Kyungwon Lee ; Jong Hwa Yum ; Yunsop Chong ; Jean-Denis Docquier ; Gian Maria Rossolini ; Seok Hoon Jeong ; Dongeun Yong 
Citation
 Antimicrobial Agents and Chemotherapy, Vol.55(12) : 5930~5932, 2011 
Journal Title
 Antimicrobial Agents and Chemotherapy 
ISSN
 0066-4804 
Issue Date
2011
Abstract
The TEM-107 extended-spectrum β-lactamase detected in a Klebsiella pneumoniae clinical isolate had a Gly238Ser substitution compared to the TEM-43 β-lactamase. The MIC of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. Clavulanic acid reduced the MIC of ceftazidime 64-fold.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94908
DOI
10.1128/AAC.05341-11
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Laboratory Medicine
Yonsei Authors
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