225 603

Cited 3 times in

Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea.

Authors
 Kyungwon Lee  ;  Jong Hwa Yum  ;  Dongeun Yong  ;  Seok Hoon Jeong  ;  Gian Maria Rossolini  ;  Jean-Denis Docquier  ;  Yunsop Chong 
Citation
 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Vol.55(12) : 5930-5932, 2011 
Journal Title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN
 0066-4804 
Issue Date
2011
MeSH
Adolescent ; Amino Acid Substitution* ; Anti-Bacterial Agents/pharmacology* ; Cefotaxime/pharmacology ; Ceftazidime/pharmacology ; Clavulanic Acid/pharmacology ; Conjugation, Genetic ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Female ; Humans ; Kinetics ; Klebsiella Infections/microbiology* ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/enzymology* ; Klebsiella pneumoniae/isolation & purification* ; Microbial Sensitivity Tests/standards ; Republic of Korea ; beta-Lactam Resistance/genetics ; beta-Lactamases/chemistry ; beta-Lactamases/genetics* ; beta-Lactamases/metabolism
Abstract
The TEM-107 extended-spectrum β-lactamase detected in a Klebsiella pneumoniae clinical isolate had a Gly238Ser substitution compared to the TEM-43 β-lactamase. The MIC of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. Clavulanic acid reduced the MIC of ceftazidime 64-fold.
Files in This Item:
T201105063.pdf Download
DOI
10.1128/AAC.05341-11
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Yong, Dong Eun(용동은) ORCID logo https://orcid.org/0000-0002-1225-8477
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
Jeong, Seok Hoon(정석훈) ORCID logo https://orcid.org/0000-0001-9290-897X
Chong, Yun Sop(정윤섭)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94908
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links