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Adiponectin is Associated with Impaired Fasting Glucose in the Non-Diabetic Population.
DC Field | Value | Language |
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dc.contributor.author | 박현경 | - |
dc.contributor.author | 윤지은 | - |
dc.contributor.author | 이선주 | - |
dc.contributor.author | 지선하 | - |
dc.date.accessioned | 2014-12-20T17:33:50Z | - |
dc.date.available | 2014-12-20T17:33:50Z | - |
dc.date.issued | 2011 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/94836 | - |
dc.description.abstract | OBJECTIVES: Adiponectin is strongly associated with diabetes in the Western population. However, whether adiponectin is independently associated with impaired fasting glucose (IFG) in the non-obese population is unknown. METHODS: The serum adiponectin, insulin resistance (IR), and waist circumference (WC) of 27,549 healthy Koreans were measured. Individuals were then classified into tertile groups by gender. IFG was defined as a fasting serum glucose of 100-125 mg/dL without diabetes. IR was calculated using the homeostasis model assessment of insulin resistance (HOMA-IR). The association of adiponectin and IFG was determined using logistic regression analysis. RESULTS: WC and adiponectin were associated with IFG in both men and women. However, the association of WC with IFG was attenuated in both men and women after adjustment for the HOMA-IR. Adiponectin was still associated with IFG after adjustment for and stratification by HOMA-IR in men and women. Strong combined associations of IR and adiponectin with IFG were observed in men and women. Multivariate adjusted odds ratios (ORs) (95% confidence interval [CI]) among those in the highest tertile of IR and the lowest tertile of adiponectin were 9.8 (7.96 to 12.07) for men and 24.1 (13.86 to 41.94) for women. CONCLUSION: These results suggest that adiponectin is strongly associated with IFG, and point to adiponectin as an additional diagnostic biomarker of IFG in the non-diabetic population. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | EPIDEMIOLOGY AND HEALTH | - |
dc.publisher | EPIDEMIOLOGY AND HEALTH | - |
dc.relation.isPartOf | EPIDEMIOLOGY AND HEALTH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Adiponectin is Associated with Impaired Fasting Glucose in the Non-Diabetic Population. | - |
dc.type | Article | - |
dc.contributor.college | Graduate School of Public Health (보건대학원) | - |
dc.contributor.department | Graduate School of Public Health (보건대학원) | - |
dc.contributor.googleauthor | Sang Yeun Kim | - |
dc.contributor.googleauthor | Sun Ju Lee | - |
dc.contributor.googleauthor | Hyoun Kyoung Park | - |
dc.contributor.googleauthor | Ji Eun Yun | - |
dc.contributor.googleauthor | Myoungsook Lee | - |
dc.contributor.googleauthor | Jidong Sung | - |
dc.contributor.googleauthor | Sun Ha Jee | - |
dc.identifier.doi | 10.4178/epih/e2011007 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01734 | - |
dc.contributor.localId | A02608 | - |
dc.contributor.localId | A03965 | - |
dc.contributor.localId | A02861 | - |
dc.relation.journalcode | J00791 | - |
dc.identifier.eissn | 2092-7193 | - |
dc.identifier.pmid | 21909476 | - |
dc.subject.keyword | Adiponectin | - |
dc.subject.keyword | Diabetes | - |
dc.subject.keyword | Impaired fasting glucose | - |
dc.subject.keyword | Insulin resistance | - |
dc.contributor.alternativeName | Park, Hyoun Kyoung | - |
dc.contributor.alternativeName | Yun, Ji Eun | - |
dc.contributor.alternativeName | Lee, Sun Ju | - |
dc.contributor.alternativeName | Jee, Sun Ha | - |
dc.contributor.affiliatedAuthor | Park, Hyoun Kyoung | - |
dc.contributor.affiliatedAuthor | Yun, Ji Eun | - |
dc.contributor.affiliatedAuthor | Jee, Sun Ha | - |
dc.contributor.affiliatedAuthor | Lee, Sun Ju | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 33 | - |
dc.citation.startPage | 2011007 | - |
dc.identifier.bibliographicCitation | EPIDEMIOLOGY AND HEALTH, Vol.33 : 2011007, 2011 | - |
dc.identifier.rimsid | 27784 | - |
dc.type.rims | ART | - |
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