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HBV genotypes: relevance to natural history, pathogenesis and treatment of chronic hepatitis B

DC Field Value Language
dc.contributor.author김범경-
dc.contributor.author안상훈-
dc.date.accessioned2014-12-20T17:33:10Z-
dc.date.available2014-12-20T17:33:10Z-
dc.date.issued2011-
dc.identifier.issn1359-6535-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/94814-
dc.description.abstractAlthough chronic HBV infection is the leading cause of chronic liver disease and death worldwide, there are substantial differences in its clinical courses regarding prevalence, mode of transmission, characteristics of each phase, responses to antiviral therapy, and development of cirrhosis and hepatocellular carcinoma, according to geographical areas (Asia versus Western Europe and North America versus Africa). Furthermore, the clinical course in infected individuals depends on a complex interplay among various factors including viral, host, environmental and other factors. Recently, understanding of molecular characteristics of the prevailing HBV genotypes, frequently accompanied mutations and their clinical implications might explain these geographical differences more pertinently. Hence, in this article, we review the global epidemiology and the natural history of HBV infection, with emphasis on summarizing the different HBV genotypes according to regions.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1169~1186-
dc.relation.isPartOfANTIVIRAL THERAPY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAfrica/epidemiology-
dc.subject.MESHAntiviral Agents/administration & dosage-
dc.subject.MESHAntiviral Agents/therapeutic use-
dc.subject.MESHAsia/epidemiology-
dc.subject.MESHCarcinoma, Hepatocellular/etiology-
dc.subject.MESHCarcinoma, Hepatocellular/virology-
dc.subject.MESHContinental Population Groups*-
dc.subject.MESHEurope/epidemiology-
dc.subject.MESHGenes, Viral/immunology*-
dc.subject.MESHGenotype-
dc.subject.MESHHepatitis B e Antigens/analysis-
dc.subject.MESHHepatitis B e Antigens/genetics-
dc.subject.MESHHepatitis B e Antigens/immunology*-
dc.subject.MESHHepatitis B virus*/classification-
dc.subject.MESHHepatitis B virus*/genetics-
dc.subject.MESHHepatitis B virus*/pathogenicity-
dc.subject.MESHHepatitis B, Chronic/complications-
dc.subject.MESHHepatitis B, Chronic/drug therapy-
dc.subject.MESHHepatitis B, Chronic/ethnology*-
dc.subject.MESHHepatitis B, Chronic/immunology-
dc.subject.MESHHepatitis B, Chronic/pathology-
dc.subject.MESHHepatitis B, Chronic/transmission-
dc.subject.MESHHepatitis B, Chronic/virology-
dc.subject.MESHHost-Pathogen Interactions-
dc.subject.MESHHumans-
dc.subject.MESHLiver Cirrhosis/etiology-
dc.subject.MESHLiver Cirrhosis/virology-
dc.subject.MESHLiver Neoplasms/etiology-
dc.subject.MESHLiver Neoplasms/virology-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMutation Rate-
dc.subject.MESHNorth America/epidemiology-
dc.subject.MESHPhylogeography-
dc.subject.MESHPrevalence-
dc.subject.MESHRisk Factors-
dc.subject.MESHYoung Adult-
dc.titleHBV genotypes: relevance to natural history, pathogenesis and treatment of chronic hepatitis B-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorBeom Kyung Kim-
dc.contributor.googleauthorPeter A Revill-
dc.contributor.googleauthorSang Hoon Ahn-
dc.identifier.doi10.3851/IMP1982-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00487-
dc.contributor.localIdA02226-
dc.relation.journalcodeJ00191-
dc.identifier.eissn2040-2058-
dc.identifier.pmid22155900-
dc.identifier.urlhttp://www.intmedpress.com/journals/avt/article.cfm?id=1982&pid=88&sType=AVT-
dc.contributor.alternativeNameKim, Beom Kyung-
dc.contributor.alternativeNameAhn, Sang Hoon-
dc.contributor.affiliatedAuthorKim, Beom Kyung-
dc.contributor.affiliatedAuthorAhn, Sang Hoon-
dc.rights.accessRightsnot free-
dc.citation.volume16-
dc.citation.number8-
dc.citation.startPage1169-
dc.citation.endPage1186-
dc.identifier.bibliographicCitationANTIVIRAL THERAPY, Vol.16(8) : 1169-1186, 2011-
dc.identifier.rimsid27771-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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