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사람면역결핍바이러스 감염 환자의 폐동맥 고혈압 발생빈도 및 임상양상
DC Field | Value | Language |
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dc.contributor.author | 최준용 | - |
dc.contributor.author | 하종원 | - |
dc.contributor.author | 한상훈 | - |
dc.contributor.author | 홍지영 | - |
dc.contributor.author | 강민경 | - |
dc.contributor.author | 김미현 | - |
dc.contributor.author | 김준명 | - |
dc.contributor.author | 신소연 | - |
dc.contributor.author | 심지영 | - |
dc.contributor.author | 양영준 | - |
dc.contributor.author | 양우인 | - |
dc.contributor.author | 장혁재 | - |
dc.contributor.author | 정남식 | - |
dc.date.accessioned | 2014-12-20T17:32:25Z | - |
dc.date.available | 2014-12-20T17:32:25Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1226-329X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/94790 | - |
dc.description.abstract | Background/Aims: Human immunodeficiency virus-associated pulmonary arterial hypertension (HIV-PAH) is a complication of HIV infection. Due to improvements in HIV survival rates following the introduction of highly active antiretroviral therapy, HIV-PAH has become an important cause of HIV-related morbidity. Thus, the objective of this study was to explore the prevalence and characteristics of HIV-PAH. Methods: Ninety-two patients were enrolled in the study from March to August 2010. We investigated clinical characteristics and performed echocardiography. HIV-PAH was defined as having a mean pulmonary arterial pressure (mPAP)≥25 mmHg based on Mahan`s equation, without lung disease or heart disease. The HIV-PAH-possible group was defined as having a tricuspid regurgitation velocity (TRV) of 2.9-3.4 m/s and a pulmonary arterial systolic pressure (PASP) of 37-50 mmHg. Results: Fifteen patients (16.3%) met the criteria of HIV-PAH based on mPAP. With respect to TRV, six patients met the criteria of the HIV-PAH-possible group. Based on the criteria of mPAP, the duration of HIV infection was not different with or without HIV-PAH. HIV RNA titers and CD4 T cell counts tended to be higher in HIV-PAH patients (8,607±11 vs. 1,067±64 copies/mL, p=0.371; 471±148 vs. 499±252 cells/mm3, p=0.680, respectively). Echocardiographic indices of the right ventricle were significantly deteriorated in the HIV-PAH group as compared with the non-HIV-PAH group (TASPE: 20.52 vs. 23.2, p=0.001; Tei index: 0.42 vs. 0.39, p=0.037). In a multivariate regression analysis, HIV activity factors (HIV duration, HIV RNA titer, and CD4 cell count) were not associated with echocardiographic indices of PAH (mPAP, PASP, and pulmonary vascular resistance). Conclusions: In this study, the prevalence of HIV-PAH was comparable to that of previous studies. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 729~739 | - |
dc.relation.isPartOf | Korean Journal of Medicine | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 사람면역결핍바이러스 감염 환자의 폐동맥 고혈압 발생빈도 및 임상양상 | - |
dc.title.alternative | Prevalence and Clinical Characteristics of Pulmonary Arterial Hypertension in Human Immunodeficiency Virus-Infected Patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | 김미현 | - |
dc.contributor.googleauthor | 장혁재 | - |
dc.contributor.googleauthor | 양영준 | - |
dc.contributor.googleauthor | 홍지영 | - |
dc.contributor.googleauthor | 강민경 | - |
dc.contributor.googleauthor | 양우인 | - |
dc.contributor.googleauthor | 심지영 | - |
dc.contributor.googleauthor | 하종원 | - |
dc.contributor.googleauthor | 정남식 | - |
dc.contributor.googleauthor | 신소연 | - |
dc.contributor.googleauthor | 한상훈 | - |
dc.contributor.googleauthor | 최준용 | - |
dc.contributor.googleauthor | 김준명 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04191 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A04286 | - |
dc.contributor.localId | A00454 | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A02116 | - |
dc.contributor.localId | A02213 | - |
dc.contributor.localId | A02298 | - |
dc.contributor.localId | A02301 | - |
dc.contributor.localId | A03490 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A04441 | - |
dc.contributor.localId | A00024 | - |
dc.relation.journalcode | J02059 | - |
dc.subject.keyword | Echocardiography | - |
dc.subject.keyword | Human immunodeficiency virus | - |
dc.subject.keyword | Pulmonary hypertension | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.alternativeName | Han, Sang Hoon | - |
dc.contributor.alternativeName | Hong, Ji Young | - |
dc.contributor.alternativeName | Kang, Min Kyung | - |
dc.contributor.alternativeName | Kim, Mi Hyun | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Shin, So Youn | - |
dc.contributor.alternativeName | Shim, Chi Young | - |
dc.contributor.alternativeName | Yang, Young June | - |
dc.contributor.alternativeName | Yang, Woo In | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Han, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Mi Hyun | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Shin, So Youn | - |
dc.contributor.affiliatedAuthor | Shim, Chi Young | - |
dc.contributor.affiliatedAuthor | Yang, Young June | - |
dc.contributor.affiliatedAuthor | Yang, Woo In | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Hong , Ji Young | - |
dc.contributor.affiliatedAuthor | Kang, Min Kyung | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 81 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 729 | - |
dc.citation.endPage | 739 | - |
dc.identifier.bibliographicCitation | Korean Journal of Medicine, Vol.81(6) : 729-739, 2011 | - |
dc.identifier.rimsid | 27755 | - |
dc.type.rims | ART | - |
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