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Evaluation of a fully automated treponemal test and comparison with conventional VDRL and FTA-ABS tests.

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dc.contributor.author김현숙-
dc.contributor.author박용정-
dc.date.accessioned2014-12-20T17:24:49Z-
dc.date.available2014-12-20T17:24:49Z-
dc.date.issued2011-
dc.identifier.issn0002-9173-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/94556-
dc.description.abstractWe evaluated analytic performances of an automated treponemal test and compared this test with the Venereal Disease Research Laboratory test (VDRL) and fluorescent treponemal antibody absorption test (FTA-ABS). Precision performance of the Architect Syphilis TP assay (TP; Abbott Japan, Tokyo, Japan) was assessed, and 150 serum samples were assayed with the TP before and after heat inactivation to estimate the effect of heat inactivation. A total of 616 specimens were tested with the FTA-ABS and TP, and 400 were examined with the VDRL. The TP showed good precision performance with total imprecision of less than a 10% coefficient of variation. An excellent linear relationship between results before and after heat inactivation was observed (R(2) = 0.9961). The FTA-ABS and TP agreed well with a κ coefficient of 0.981. The concordance rate between the FTA-ABS and TP was the highest (99.0%), followed by the rates between FTA-ABS and VDRL (85.0%) and between TP and VDRL (83.8%). The automated TP assay may be adequate for screening for syphilis in a large volume of samples and can be an alternative to FTA-ABS.-
dc.description.statementOfResponsibilityopen-
dc.format.extent705~710-
dc.relation.isPartOfAMERICAN JOURNAL OF CLINICAL PATHOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHFemale-
dc.subject.MESHFluorescent Treponemal Antibody-Absorption Test/methods-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHSyphilis/diagnosis*-
dc.subject.MESHSyphilis Serodiagnosis/methods*-
dc.subject.MESHTreponema Immobilization Test/methods-
dc.subject.MESHTreponema pallidum/isolation & purification*-
dc.titleEvaluation of a fully automated treponemal test and comparison with conventional VDRL and FTA-ABS tests.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorYongjung Park-
dc.contributor.googleauthorYounhee Park-
dc.contributor.googleauthorShin Young Joo-
dc.contributor.googleauthorMyoung Hee Park-
dc.contributor.googleauthorHyon-Suk Kim-
dc.identifier.doi10.1309/AJCP0WOK0QDYGDCM-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01582-
dc.contributor.localIdA01117-
dc.relation.journalcodeJ00076-
dc.identifier.eissn1943-7722-
dc.identifier.pmid22031308-
dc.subject.keywordSyphilis-
dc.subject.keywordTreponemal test-
dc.subject.keywordArchitect Syphilis TP assay-
dc.subject.keywordVenereal Disease Research Laboratory test-
dc.subject.keywordVDRL test-
dc.subject.keywordFluorescent treponemal antibody absorption test-
dc.subject.keywordFTA-ABS test-
dc.contributor.alternativeNameKim, Hyon Suk-
dc.contributor.alternativeNamePark, Yong Jung-
dc.contributor.affiliatedAuthorPark, Yong Jung-
dc.contributor.affiliatedAuthorKim, Hyon Suk-
dc.rights.accessRightsfree-
dc.citation.volume136-
dc.citation.number5-
dc.citation.startPage705-
dc.citation.endPage710-
dc.identifier.bibliographicCitationAMERICAN JOURNAL OF CLINICAL PATHOLOGY, Vol.136(5) : 705-710, 2011-
dc.identifier.rimsid27415-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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