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유두상 갑상선암의 경부 림프절 전이 진단을 위한 미세침 흡인 세척액 갑상선글로불린 검사의 유용성
DC Field | Value | Language |
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dc.contributor.author | 김신영 | - |
dc.contributor.author | 최승준 | - |
dc.date.accessioned | 2014-12-20T17:20:37Z | - |
dc.date.available | 2014-12-20T17:20:37Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 2093-6338 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/94422 | - |
dc.description.abstract | BACKGROUND: Previous studies have shown that thyroglobulin (Tg) measurement in fine-needle aspirates (FNA) of lymph nodes can assist in evaluating cervical lymph node metastasis. In this study, we evaluated the diagnostic performances of FNA-Tg, serum-Tg, and FNA-Tg/serum-Tg in detecting lymph node metastasis. METHODS: We retrospectively analyzed the diagnostic performances of FNA-Tg and serum-Tg in 641 cases (518 patients) with papillary thyroid cancer that underwent ultrasonography-guided fine-needle aspiration of cervical lymph nodes between March 2009 and February 2010. RESULTS: The number of lymph nodes and median FNA-Tg level of the positive lymph node cytology group were 99 and 1,300 ng/mL (range, 0.2-5,000), respectively, whereas corresponding values in the negative cytology group were 359 and 4.7 ng/mL (range, 0.1-1,173). The AUCs of FNA-Tg, serum-Tg, and FNA-Tg/serum-Tg ratio were 0.93 (95% CI, 0.90-0.97), 0.64 (95% CI, 0.57-0.70), and 0.83 (95% CI, 0.78-0.88), respectively. The sensitivity and specificity of FNA-Tg were 90.9% and 98.3%, respectively, and the percentage agreement with the cytology results was 96.7%. CONCLUSIONS: The agreement of FNA-Tg with the cytology results was good at the cutoff value of 35.9 ng/mL. The measurement of FNA-Tg in cases with uninterpretable cytology results can be useful in evaluating lymph node metastasis of papillary thyroid cancer | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | Laboratory Medicine Online | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 유두상 갑상선암의 경부 림프절 전이 진단을 위한 미세침 흡인 세척액 갑상선글로불린 검사의 유용성 | - |
dc.title.alternative | Usefulness of Thyroglobulin Measurement in Fine-needle Aspirates of Lymph Nodes for the Diagnosis of Lymph Node Metastasis of Papillary Thyroid Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | 홍덕진 | - |
dc.contributor.googleauthor | 최승준 | - |
dc.contributor.googleauthor | 김신영 | - |
dc.identifier.doi | 10.3343/lmo.2011.1.3.2 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00675 | - |
dc.relation.journalcode | J02151 | - |
dc.subject.keyword | Thyroid cancer | - |
dc.subject.keyword | Thyroglobulin | - |
dc.subject.keyword | Lymph node | - |
dc.subject.keyword | Fine-needle aspiration | - |
dc.contributor.alternativeName | Kim, Sin Young | - |
dc.contributor.affiliatedAuthor | Kim, Sin Young | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 1 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 132 | - |
dc.citation.endPage | 137 | - |
dc.identifier.bibliographicCitation | Laboratory Medicine Online, Vol.1(3) : 132-137, 2011 | - |
dc.identifier.rimsid | 27606 | - |
dc.type.rims | ART | - |
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