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Clinical profile of autoimmune pancreatitis and its histological subtypes: an international multicenter survey

DC FieldValueLanguage
dc.contributor.author정재복-
dc.date.accessioned2014-12-20T17:17:09Z-
dc.date.available2014-12-20T17:17:09Z-
dc.date.issued2011-
dc.identifier.issn0885-3177-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/94309-
dc.description.abstractOBJECTIVE: The objective of this study was to clarify the clinical and pathophysiological characteristics of autoimmune pancreatitis (AIP) and its subtypes (lymphoplasmacytic sclerosing pancreatitis [LPSP] and idiopathic duct-centric pancreatitis [IDCP]) seen around the world. METHODS: An international multicenter survey of AIP was conducted in 15 institutes from 8 countries. We compared clinical and pathologic profiles of AIP (n = 731) and the clinical profiles of LPSP (n = 204) and IDCP (n = 64) patients. RESULTS: Patients with LPSP were approximately 16 years older than IDCP patients. Obstructive jaundice was a more frequent presentation in LPSP versus IDCP (75% vs 47%, P < 0.001), whereas abdominal pain (41% vs 68%, P < 0.001) and acute pancreatitis (5% vs 34%, P < 0.001) were more frequent in IDCP patients. Patients with LPSP were more likely to have diffuse swelling of the pancreas (40% vs 25%, P = 0.037) and elevated serum IgG4 levels (63% vs 23%, P < 0.001) but less likely to be associated with ulcerative colitis (1% vs 16%, P < 0.001). Clinical profiles of non-histologically confirmed AIP from Asia, the United States, and United Kingdom corresponded with that of LPSP, whereas those from Italy and Germany suggested a mixture of LPSP and IDCP. CONCLUSIONS: Autoimmune pancreatitis is seen all around the world, with regional differences in the pathologic and clinical features. Lymphoplasmacytic sclerosing pancreatitis and IDCP have distinct clinical profiles.-
dc.description.statementOfResponsibilityopen-
dc.format.extent809~814-
dc.relation.isPartOfPancreas-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAbdominal Pain/etiology-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAutoimmune Diseases/classification-
dc.subject.MESHAutoimmune Diseases/complications-
dc.subject.MESHAutoimmune Diseases/pathology*-
dc.subject.MESHData Collection-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInflammatory Bowel Diseases/complications-
dc.subject.MESHJaundice, Obstructive/etiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPancreatitis/classification-
dc.subject.MESHPancreatitis/complications-
dc.subject.MESHPancreatitis/pathology*-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSclerosis-
dc.subject.MESHSteroids/therapeutic use-
dc.titleClinical profile of autoimmune pancreatitis and its histological subtypes: an international multicenter survey-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorTerumi Kamisawa-
dc.contributor.googleauthorSuresh T. Chari-
dc.contributor.googleauthorSamuel A. Giday-
dc.contributor.googleauthorMyung-Hwan Kim-
dc.contributor.googleauthorJae Bock Chung-
dc.contributor.googleauthorKyu Taek Lee-
dc.contributor.googleauthorJens Werner-
dc.contributor.googleauthorFrank Bergmann-
dc.contributor.googleauthorMarkus M. Lerch-
dc.contributor.googleauthorJulia Mayerle-
dc.contributor.googleauthorTilman Pickartz-
dc.contributor.googleauthorMatthias Lohr-
dc.contributor.googleauthorAlexander Schneider-
dc.contributor.googleauthorLuca Frulloni-
dc.contributor.googleauthorGeorge J. M. Webster-
dc.contributor.googleauthorD. Nageshwar Reddy-
dc.contributor.googleauthorWei-Chih Liao-
dc.contributor.googleauthorHsiu-Po Wang-
dc.contributor.googleauthorKazuichi Okazaki-
dc.contributor.googleauthorTooru Shimosegawa-
dc.contributor.googleauthorGuenter Kloeppel-
dc.contributor.googleauthorVay Liang W. Go-
dc.identifier.doi10.1097/MPA.0b013e3182258a15-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03706-
dc.relation.journalcodeJ02463-
dc.identifier.pmid21747310-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00006676-201108000-00002&LSLINK=80&D=ovft-
dc.subject.keywordlymphoplasmacytic sclerosing pancreatitis-
dc.subject.keywordidiopathic duct-centric pancreatitis-
dc.subject.keywordIgG4-
dc.subject.keywordchronic pancreatitis-
dc.contributor.alternativeNameChung, Jae Bock-
dc.contributor.affiliatedAuthorChung, Jae Bock-
dc.rights.accessRightsnot free-
dc.citation.volume40-
dc.citation.number6-
dc.citation.startPage809-
dc.citation.endPage814-
dc.identifier.bibliographicCitationPancreas, Vol.40(6) : 809-814, 2011-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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