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Isolation of a Klebsiella pneumoniae isolate of sequence type 258 producing KPC-2 carbapenemase in Korea

DC Field Value Language
dc.contributor.author이경원-
dc.contributor.author용동은-
dc.date.accessioned2014-12-20T17:12:08Z-
dc.date.available2014-12-20T17:12:08Z-
dc.date.issued2011-
dc.identifier.issn1598-6535-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/94150-
dc.description.abstractCarbapenem-resistant Klebsiella pneumoniae isolates producing K. pneumoniae carbapenemases (KPC) were first reported in the USA in 2001, and since then, this infection has been reported in Europe, Israel, South America, and China. In Korea, the first KPC-2-producing K. pneumoniae sequence type (ST) 11 strain was detected in 2010. We report the case of a patient with a urinary tract infection caused by KPC-2-producing K. pneumoniae. This is the second report of a KPC-2-producing K. pneumoniae infection in Korea, but the multilocus sequence type was ST258. The KPC-2-producing isolate was resistant to all tested β-lactams (including imipenem and meropenem), amikacin, tobramycin, ciprofloxacin, levofloxacin, and trimethoprim-sulfamethoxazole, but was susceptible to gentamicin, colistin, polymyxin B, and tigecycline. The KPC-2-producing isolate was negative to phenotypic extended-spectrum β-lactamase (ESBL) and AmpC detection tests and positive to modified Hodge test and carbapenemase inhibition test with aminophenylboronic acid.-
dc.description.statementOfResponsibilityopen-
dc.format.extent298~301-
dc.relation.isPartOfKOREAN JOURNAL OF LABORATORY MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBacterial Proteins/antagonists & inhibitors-
dc.subject.MESHBacterial Proteins/metabolism-
dc.subject.MESHCarbapenems/pharmacology-
dc.subject.MESHDrug Resistance, Bacterial/genetics-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKlebsiellapneumoniae/drug effects-
dc.subject.MESHKlebsiellapneumoniae/genetics-
dc.subject.MESHKlebsiellapneumoniae/isolation& purification*-
dc.subject.MESHMicrobial Sensitivity Tests-
dc.subject.MESHRepublic ofKorea-
dc.subject.MESHSequenceAnalysis, DNA-
dc.subject.MESHUrinary Tract Infections/diagnosis*-
dc.subject.MESHUrinary Tract Infections/microbiology-
dc.subject.MESHbeta-Lactamase Inhibitors-
dc.subject.MESHbeta-Lactamases/biosynthesis-
dc.subject.MESHbeta-Lactamases/genetics*-
dc.subject.MESHbeta-Lactamases/metabolism-
dc.titleIsolation of a Klebsiella pneumoniae isolate of sequence type 258 producing KPC-2 carbapenemase in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorKyoung Ho Roh-
dc.contributor.googleauthorChang Kyu Lee-
dc.contributor.googleauthorJang Wook Sohn-
dc.contributor.googleauthorWonkeun Song-
dc.contributor.googleauthorDongeun Yong-
dc.contributor.googleauthorKyungwon Lee-
dc.identifier.doi10.3343/kjlm.2011.31.4.298-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02649-
dc.contributor.localIdA02423-
dc.relation.journalcodeJ02044-
dc.identifier.pmid22016687-
dc.subject.keywordKPC-2-
dc.subject.keywordKlebsiellapneumoniae-
dc.subject.keywordST258-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.rights.accessRightsfree-
dc.citation.volume31-
dc.citation.number4-
dc.citation.startPage298-
dc.citation.endPage301-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF LABORATORY MEDICINE , Vol.31(4) : 298-301, 2011-
dc.identifier.rimsid27273-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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