Cited 16 times in
Prognostic utility of changes in N-terminal pro-brain natriuretic Peptide combined with sequential organ failure assessment scores in patients with acute lung injury/acute respiratory distress syndrome concomitant with septic shock.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강영애 | - |
dc.contributor.author | 김세규 | - |
dc.contributor.author | 김영삼 | - |
dc.contributor.author | 김은영 | - |
dc.contributor.author | 박무석 | - |
dc.contributor.author | 박병훈 | - |
dc.contributor.author | 임주은 | - |
dc.contributor.author | 장준 | - |
dc.contributor.author | 정지예 | - |
dc.date.accessioned | 2014-12-20T17:10:26Z | - |
dc.date.available | 2014-12-20T17:10:26Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1073-2322 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/94096 | - |
dc.description.abstract | We investigated the prognostic utility of changes in N-terminal pro-brain natriuretic peptide (NT-proBNP) in combination with Sequential Organ Failure Assessment (SOFA) score in patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) concomitant with septic shock. Forty-nine mechanically ventilated patients with ALI/ARDS concomitant with septic shock were studied. N-terminal pro-brain natriuretic peptide levels were measured on the first 3 days (days 0, 1, and 2) in the intensive care unit. The median NT-proBNP levels in survivors and nonsurvivors were 3,999 vs. 2,819 pg/mL on day 0 (P = 0.719); 4,495 vs. 5,397 pg/mL on day 1 (P = 0.543); and 2,325 vs. 14,173 pg/mL on day 2 (P = 0.028). N-terminal pro-brain natriuretic peptide levels increased significantly from baseline values in nonsurvivors only. We observed a monotonic increase in 28-day mortality associated with increasing quartiles of percent change in NT-proBNP on day 2 (P < 0.0001). Kaplan-Meier survival analysis revealed that mortality was significantly higher in patients with a change in NT-proBNP of 30% or more (log-rank P < 0.0001). On day 2, areas under the receiver operating characteristic curves for predicting 28-day mortality were 0.74 for SOFA alone and 0.85 (P = 0.028) for SOFA combined with percent change in NT-proBNP. In conclusion, in patients with ALI/ARDS concomitant with septic shock, a rising trend (high percent change) in NT-proBNP levels had better prognostic utility than absolute levels. The combination of percent change in NT-proBNP with SOFA may provide superior prognostic accuracy to SOFA alone. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 109~114 | - |
dc.relation.isPartOf | SHOCK | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | AcuteLungInjury/blood* | - |
dc.subject.MESH | AcuteLungInjury/pathology | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | NatriureticPeptide, Brain/blood* | - |
dc.subject.MESH | PeptideFragments/blood* | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | RespiratoryDistressSyndrome, Adult/blood* | - |
dc.subject.MESH | RespiratoryDistressSyndrome, Adult/pathology | - |
dc.subject.MESH | Shock,Septic/blood* | - |
dc.subject.MESH | Shock,Septic/pathology | - |
dc.title | Prognostic utility of changes in N-terminal pro-brain natriuretic Peptide combined with sequential organ failure assessment scores in patients with acute lung injury/acute respiratory distress syndrome concomitant with septic shock. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Byung Hoon Park | - |
dc.contributor.googleauthor | Moo Suk Park | - |
dc.contributor.googleauthor | Young Sam Kim | - |
dc.contributor.googleauthor | Se Kyu Kim | - |
dc.contributor.googleauthor | Young Ae Kang | - |
dc.contributor.googleauthor | Ji Ye Jung | - |
dc.contributor.googleauthor | Ju Eun Lim | - |
dc.contributor.googleauthor | Eun Young Kim | - |
dc.contributor.googleauthor | Joon Chang | - |
dc.identifier.doi | 10.1097/SHK.0b013e31821d8f2d | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00057 | - |
dc.contributor.localId | A00602 | - |
dc.contributor.localId | A00707 | - |
dc.contributor.localId | A01457 | - |
dc.contributor.localId | A01478 | - |
dc.contributor.localId | A03407 | - |
dc.contributor.localId | A03472 | - |
dc.contributor.localId | A03735 | - |
dc.contributor.localId | A00811 | - |
dc.relation.journalcode | J02658 | - |
dc.identifier.eissn | 1540-0514 | - |
dc.identifier.pmid | 21478812 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00024382-201108000-00003&LSLINK=80&D=ovft | - |
dc.subject.keyword | B-type natriuretic peptide | - |
dc.subject.keyword | survival | - |
dc.subject.keyword | prognosis | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | intensive care | - |
dc.contributor.alternativeName | Kang, Young Ae | - |
dc.contributor.alternativeName | Kim, Se Kyu | - |
dc.contributor.alternativeName | Kim, Young Sam | - |
dc.contributor.alternativeName | Kim, Eun Young | - |
dc.contributor.alternativeName | Park, Moo Suk | - |
dc.contributor.alternativeName | Park, Byung Hoon | - |
dc.contributor.alternativeName | Lim, Ju Eun | - |
dc.contributor.alternativeName | Chang, Joon | - |
dc.contributor.alternativeName | Jung, Ji Ye | - |
dc.contributor.affiliatedAuthor | Kang, Young Ae | - |
dc.contributor.affiliatedAuthor | Kim, Se Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Young Sam | - |
dc.contributor.affiliatedAuthor | Park, Moo Suk | - |
dc.contributor.affiliatedAuthor | Park, Byung Hoon | - |
dc.contributor.affiliatedAuthor | Lim, Ju Eun | - |
dc.contributor.affiliatedAuthor | Chang, Joon | - |
dc.contributor.affiliatedAuthor | Jung, Ji Ye | - |
dc.contributor.affiliatedAuthor | Kim, Eun Young | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 36 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 109 | - |
dc.citation.endPage | 114 | - |
dc.identifier.bibliographicCitation | SHOCK, Vol.36(2) : 109-114, 2011 | - |
dc.identifier.rimsid | 27236 | - |
dc.type.rims | ART | - |
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