Cited 23 times in
Risk factors for false-negative results of QuantiFERON-TB Gold In-Tube assay in non-HIV-infected patients with culture-confirmed tuberculosis.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강영애 | - |
dc.contributor.author | 김세규 | - |
dc.contributor.author | 김영삼 | - |
dc.contributor.author | 김은영 | - |
dc.contributor.author | 박무석 | - |
dc.contributor.author | 장준 | - |
dc.date.accessioned | 2014-12-20T17:09:22Z | - |
dc.date.available | 2014-12-20T17:09:22Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0732-8893 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/94063 | - |
dc.description.abstract | Limited information is available on the risk factors for false-negative results with the new generation of QuantiFERON-TB Gold In-Tube (QFT-GIT) tests in non-HIV-infected patients with tuberculosis (TB). We sought to identify risk factors for false-negative QFT-GIT results in culture-confirmed TB patients. We reviewed the microbiological, laboratory, radiographic, and clinical data of 362 patients with positive M. tuberculosis cultures who received QFT-GIT tests at a Korean tertiary hospital between September 2006 and March 2010. Of these, 311 (85.9%) had true-positive and 51 (14.1%) had false-negative results. The false-negative group was more likely to have immunosuppressant diseases and lower platelet, protein, and albumin levels than the true-positive group. An immunosuppressive condition was an independent risk factor for false-negative QFT-GIT results in non-HIV-infected patients with active TB (odds ratio, 2.98; 95% confidence interval, 1.38-6.47; P = .006). Careful interpretation of negative QFT-GIT results is thus necessary in immunocompromised patients suspected of having active TB | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 324~329 | - |
dc.relation.isPartOf | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Clinical Laboratory Techniques/methods* | - |
dc.subject.MESH | False Negative Reactions* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hospitals | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunoassay/methods | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Tuberculosis/diagnosis* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Risk factors for false-negative results of QuantiFERON-TB Gold In-Tube assay in non-HIV-infected patients with culture-confirmed tuberculosis. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Eun Young Kim | - |
dc.contributor.googleauthor | Moo Suk Park | - |
dc.contributor.googleauthor | Young Sam Kim | - |
dc.contributor.googleauthor | Se Kyu Kim | - |
dc.contributor.googleauthor | Joon Chang | - |
dc.contributor.googleauthor | Young Ae Kang | - |
dc.identifier.doi | 10.1016/j.diagmicrobio.2011.02.011 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00057 | - |
dc.contributor.localId | A00602 | - |
dc.contributor.localId | A00707 | - |
dc.contributor.localId | A01457 | - |
dc.contributor.localId | A03472 | - |
dc.contributor.localId | A00811 | - |
dc.relation.journalcode | J00731 | - |
dc.identifier.eissn | 1879-0070 | - |
dc.identifier.pmid | 21546200 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0732889311000940 | - |
dc.subject.keyword | Diagnosis | - |
dc.subject.keyword | False negative | - |
dc.subject.keyword | QuantiFERON-TB Gold In-Tube | - |
dc.subject.keyword | Tuberculosis | - |
dc.contributor.alternativeName | Kang, Young Ae | - |
dc.contributor.alternativeName | Kim, Se Kyu | - |
dc.contributor.alternativeName | Kim, Young Sam | - |
dc.contributor.alternativeName | Kim, Eun Young | - |
dc.contributor.alternativeName | Park, Moo Suk | - |
dc.contributor.alternativeName | Chang, Joon | - |
dc.contributor.affiliatedAuthor | Kang, Young Ae | - |
dc.contributor.affiliatedAuthor | Kim, Se Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Young Sam | - |
dc.contributor.affiliatedAuthor | Park, Moo Suk | - |
dc.contributor.affiliatedAuthor | Chang, Joon | - |
dc.contributor.affiliatedAuthor | Kim, Eun Young | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 70 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 324 | - |
dc.citation.endPage | 329 | - |
dc.identifier.bibliographicCitation | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.70(3) : 324-329, 2011 | - |
dc.identifier.rimsid | 27209 | - |
dc.type.rims | ART | - |
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