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The association between arterial stiffness and colorectal adenomatous polyp in women

Authors
 Hong-Bae Kim  ;  Hye-Ree Lee  ;  Yong-Jae Lee  ;  Dong-Hyuk Jung  ;  Byoung-Jin Park  ;  Ha-young Na  ;  Jae-Yong Shim 
Citation
 Journal of Women's Health, Vol.20(5) : 765-769, 2011 
Journal Title
 Journal of Women's Health 
ISSN
 1540-9996 
Issue Date
2011
Abstract
BACKGROUND: Colorectal adenomatous polyp is a precancerous lesion, and some studies have documented its link with cardiovascular risk factors. This study aimed to investigate the association between arterial stiffness and colorectal adenomatous polyp. METHODS: Among 388 Korean women, we examined the association between brachial-ankle pulse wave velocity (baPWV) as a measurement of arterial stiffness and the presence of colorectal adenomatous polyp as determined by colonoscopy. baPWV values were categorized separately as follows: ≤1199 cm/s, 1200-1399 cm/s, 1400-1599 cm/s and ≥1600 cm/s. The odds ratios (ORs) and 95% confidence intervals (CIs) for colorectal adenomatous polyp were calculated across each group of PWVs. RESULTS: The prevalence of colorectal adenomatous polyp was 9.5%. After adjusting for age, body mass index (BMI), cigarette smoking, blood pressure, fasting plasma glucose, and triglycerides, the ORs (95% CIs) for colorectal adenomatous polyp according to each of the four groups of baPWV were 1.00, 2.89 (0.52-15.98), 3.27 (0.48-22.24), and 11.17 (1.17-106.99). CONCLUSIONS: A higher level of baPWV was found to be independently associated with the presence of colorectal adenomatous polyp, regardless of classic cardiovascular risk factors and other components of metabolic syndrome in women
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94040
DOI
10.1089/jwh.2010.2538
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실)
Yonsei Authors
나하영(Na, Ha Young) ; 박병진(Park, Byoung Jin) ; 심재용(Shim, Jae Yong) ; 이용제(Lee, Yong Jae) ; 이혜리(Lee, Hye Ree) ; 정동혁(Jung, Dong Hyuk)
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Full Text
http://online.liebertpub.com/doi/abs/10.1089/jwh.2010.2538
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