Cited 18 times in
Clinical significance of serum sRAGE and esRAGE in women with normal pregnancy and preeclampsia
DC Field | Value | Language |
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dc.contributor.author | 권자영 | - |
dc.contributor.author | 권재현 | - |
dc.contributor.author | 김영한 | - |
dc.contributor.author | 박용원 | - |
dc.date.accessioned | 2014-12-20T17:03:45Z | - |
dc.date.available | 2014-12-20T17:03:45Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0300-5577 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93889 | - |
dc.description.abstract | BACKGROUND: We determined serum endogenous secretory receptor of advanced glycation end products (esRAGE) and soluble RAGE (sRAGE) concentrations and the esRAGE/sRAGE ratio in normal pregnancy and preeclampsia because esRAGE and sRAGE have been negatively linked to components of metabolic syndromes and pathologic pregnancy including preeclampsia. METHOD: Eighty-seven normal pregnant women and 28 with preeclampsia were recruited. Serum sRAGE and esRAGE levels were measured by enzyme-linked immunosorbent assay. RESULTS: There were significant differences in esRAGE concentration and esRAGE/sRAGE ratio between 1(st) and 3(rd) trimester in normal pregnancy (P=0.007 and P=0.003). Serum esRAGE concentrations and esRAGE/sRAGE ratio in patients with preeclampsia significantly increased compared to controls (P=0.005 and P<0.001). CONCLUSIONS: Maternal serum esRAGE concentration and esRAGE/sRAGE ratio (1) gradually decrease with gestational age in normal pregnancy; and (2) are higher in patients with preeclampsia than healthy pregnant controls, significantly. Serum esRAGE and esRAGE/sRAGE ratio might be associated with preeclampsia. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 507~513 | - |
dc.relation.isPartOf | JOURNAL OF PERINATAL MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Enzyme-Linked Immunosorbent Assay | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Pre-Eclampsia/blood* | - |
dc.subject.MESH | Pregnancy/blood* | - |
dc.subject.MESH | Pregnancy Trimester, First/blood | - |
dc.subject.MESH | Pregnancy Trimester, Third/blood | - |
dc.subject.MESH | Receptor for Advanced Glycation End Products | - |
dc.subject.MESH | Receptors, Immunologic/blood* | - |
dc.subject.MESH | Reference Values | - |
dc.subject.MESH | Solubility | - |
dc.title | Clinical significance of serum sRAGE and esRAGE in women with normal pregnancy and preeclampsia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology (산부인과학) | - |
dc.contributor.googleauthor | Jae-Hyun Kwon | - |
dc.contributor.googleauthor | Young-Han Kim | - |
dc.contributor.googleauthor | Ja-Young Kwon | - |
dc.contributor.googleauthor | Yong-Won Park | - |
dc.identifier.doi | 10.1515/jpm.2011.055 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00246 | - |
dc.contributor.localId | A00248 | - |
dc.contributor.localId | A00730 | - |
dc.contributor.localId | A01581 | - |
dc.relation.journalcode | J01693 | - |
dc.identifier.eissn | 1619-3997 | - |
dc.identifier.pmid | 21767223 | - |
dc.identifier.url | http://www.degruyter.com/view/j/jpme.2011.39.issue-5/jpm.2011.055/jpm.2011.055.xml | - |
dc.subject.keyword | esRAGE | - |
dc.subject.keyword | preeclampsia | - |
dc.subject.keyword | sRAGE | - |
dc.contributor.alternativeName | Kwon, Ja Young | - |
dc.contributor.alternativeName | Kwon, Jae Hyun | - |
dc.contributor.alternativeName | Kim, Young Han | - |
dc.contributor.alternativeName | Park, Yong Won | - |
dc.contributor.affiliatedAuthor | Kwon, Ja Young | - |
dc.contributor.affiliatedAuthor | Kwon, Jae Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Young Han | - |
dc.contributor.affiliatedAuthor | Park, Yong Won | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 39 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 507 | - |
dc.citation.endPage | 513 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERINATAL MEDICINE, Vol.39(5) : 507-513, 2011 | - |
dc.identifier.rimsid | 28528 | - |
dc.type.rims | ART | - |
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