Cited 15 times in
Incidence of subclinical coronary atherosclerosis in patients with suspected embolic stroke using cardiac computed tomography
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 장혁재 | - |
dc.date.accessioned | 2014-12-20T16:58:03Z | - |
dc.date.available | 2014-12-20T16:58:03Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1569-5794 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93717 | - |
dc.description.abstract | The purpose of this study was to investigate the incidence of subclinical coronary artery disease (CAD) in patients with suspected acute embolic stroke or transient ischemic attack (TIA) using 64-row multi-slice computed tomography (MSCT) and to examine its association with conventional risk stratification. We consecutively enrolled 175 patients (66 ± 13 years, 50% men) suspected to have had embolic stroke/TIA clinically or radiologically, and underwent 64-row MSCT to evaluate for a possible cardiac source of embolism. Both coronary artery calcium scoring (CACS) and coronary CT angiography (CCTA) were concurrently performed based on standard scanning protocols. Patients with a history of angina or documented CAD, and those with significant carotid stenosis were excluded. Atherosclerotic plaques were indentified in 105 (60%) individuals; 37 (21%) had occult CAD of ≥50% diameter stenosis on CCTA. Subjects with and without ≥50% occult CAD on CCTA had similar prevalence of cardiovascular risk factors. Thirty out of 175 (17%) individuals with ≥50% occult CAD would have missed further cardiac testing based on the American Heart association and the American Stroke Association guideline. However, these numbers would be reduced to 2% (4/175) using CACS. In logistic regression analysis, only CACS independently predicted the presence ≥50% occult CAD evidenced by CCTA. Subclinical CAD, including ≥50% stenotic disease, is highly prevalent in patients who had suffered a suspected embolic stroke. The current guideline for further cardiac testing may have limited value to identify patients with ≥50% CAD in this patient population, which can be improved by adopting CACS. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1035~1044 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Asymptomatic Diseases | - |
dc.subject.MESH | Chi-Square Distribution | - |
dc.subject.MESH | Coronary Angiography/methods* | - |
dc.subject.MESH | Coronary Artery Disease/diagnostic imaging* | - |
dc.subject.MESH | Coronary Artery Disease/epidemiology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Intracranial Embolism/epidemiology* | - |
dc.subject.MESH | Ischemic Attack, Transient/epidemiology* | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Odds Ratio | - |
dc.subject.MESH | Practice Guidelines as Topic | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Registries | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Stroke/epidemiology* | - |
dc.subject.MESH | Tomography, X-Ray Computed* | - |
dc.subject.MESH | Vascular Calcification/diagnostic imaging* | - |
dc.subject.MESH | Vascular Calcification/epidemiology | - |
dc.title | Incidence of subclinical coronary atherosclerosis in patients with suspected embolic stroke using cardiac computed tomography | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Yeonyee E. Yoon | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | Iksung Cho | - |
dc.contributor.googleauthor | Ki-Hyun Jeon | - |
dc.contributor.googleauthor | Eun-Ju Chun | - |
dc.contributor.googleauthor | Sang-il Choi | - |
dc.contributor.googleauthor | Hee-Jun Bae | - |
dc.contributor.googleauthor | Juan J. Rivera | - |
dc.contributor.googleauthor | Khurram Nasir | - |
dc.contributor.googleauthor | Roger S. Blumenthal | - |
dc.contributor.googleauthor | Tae-Hwan Lim | - |
dc.identifier.doi | 10.1007/s10554-010-9743-8 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03490 | - |
dc.relation.journalcode | J01094 | - |
dc.identifier.eissn | 1875-8312 | - |
dc.identifier.pmid | 21063781 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs10554-010-9743-8 | - |
dc.subject.keyword | Stroke | - |
dc.subject.keyword | Coronary artery disease | - |
dc.subject.keyword | Cardiac computed tomography | - |
dc.subject.keyword | Diagnosis | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 27 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1035 | - |
dc.citation.endPage | 1044 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, Vol.27(7) : 1035-1044, 2011 | - |
dc.identifier.rimsid | 28414 | - |
dc.type.rims | ART | - |
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