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Relationship between N-terminal pro-B-type natriuretic peptide and renal function: the effects on predicting early outcome after off-pump coronary artery bypass surgery.

DC Field Value Language
dc.contributor.author곽영란-
dc.contributor.author최용선-
dc.date.accessioned2014-12-20T16:55:07Z-
dc.date.available2014-12-20T16:55:07Z-
dc.date.issued2011-
dc.identifier.issn2005-6419-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/93626-
dc.description.abstractBACKGROUND: Plasma levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) provide useful prognostic predictors in patients after cardiac surgery. However, predictive accuracy of NT-proBNP levels has varied significantly according to renal dysfunction. The purpose of this study was to assess whether preoperative NT-proBNP levels could be used as predictors of early postoperative outcomes on the basis of renal function in patients undergoing off-pump coronary artery bypass surgery (OPCAB). METHODS: In 219 patients undergoing elective OPCAB, NT-proBNP and an estimated glomerular filtration rate (eGFR) were assessed preoperatively. All patients were divided into 3 groups according to tertiles of eGFR: the first (eGFR ≥ 90 ml/min/1.73 m(2)), the second (90 ml/min/1.73 m(2) > eGFR ≥ 72 ml/min/1.73 m(2)) and the third tertile group (eGFR < 72 ml/min/1.73 m(2)). End point was the composite of early postoperative complications defined as myocardial infarction, new onset atrial fibrillation, ventricular dysfunction, prolonged mechanical ventilator care (> 48 hr), prolonged ICU stay (≥ 3 days), and in hospital mortality. RESULTS: There was no difference in early postoperative complications among groups. A preoperative NT-proBNP level of 228 pg/ml and 302 pg/ml (sensitivity 70%, specificity 67%, P < 0.001 and sensitivity 73%, specificity 63%, P = 0.001, respectively) were optimal cut-off values predicting complicated early postoperative course in second and third tertile group, respectively. CONCLUSIONS: Preoperative NT-proBNP levels seem to be predictive of early postoperative complications in patients with eGFR < 90 ml/min/1.73 m(2) undergoing OPCAB.-
dc.description.statementOfResponsibilityopen-
dc.format.extent35~41-
dc.relation.isPartOfKOREAN JOURNAL OF ANESTHESIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleRelationship between N-terminal pro-B-type natriuretic peptide and renal function: the effects on predicting early outcome after off-pump coronary artery bypass surgery.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthorYoun Yi Jo-
dc.contributor.googleauthorYoung Lan Kwak-
dc.contributor.googleauthorJonghoon Lee-
dc.contributor.googleauthorYong Seon Choi-
dc.identifier.doi10.4097/kjae.2011.61.1.35-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00172-
dc.contributor.localIdA04119-
dc.relation.journalcodeJ01963-
dc.identifier.eissn2005-7563-
dc.identifier.pmid21860749-
dc.subject.keywordNT-proBNP-
dc.subject.keywordOPCAB-
dc.subject.keywordRenal function-
dc.contributor.alternativeNameKwak, Young Lan-
dc.contributor.alternativeNameChoi, Yong Seon-
dc.contributor.affiliatedAuthorKwak, Young Lan-
dc.contributor.affiliatedAuthorChoi, Yong Seon-
dc.rights.accessRightsfree-
dc.citation.volume61-
dc.citation.number1-
dc.citation.startPage35-
dc.citation.endPage41-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF ANESTHESIOLOGY, Vol.61(1) : 35-41, 2011-
dc.identifier.rimsid28351-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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