Cited 3 times in
Topiramate on the quality of life in childhood epilepsy.
DC Field | Value | Language |
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dc.contributor.author | 김흥동 | - |
dc.date.accessioned | 2014-12-20T16:52:58Z | - |
dc.date.available | 2014-12-20T16:52:58Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0387-7604 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93558 | - |
dc.description.abstract | This study evaluated the effect of topiramate (TPM) on the quality of life (QOL) in childhood epilepsy, using the Korean quality of life in childhood epilepsy (K-QOLCE) questionnaire. An open label, prospective, observational study of the families of 664 children with epilepsy from 41 centers was conducted. The parents completed the K-QOLCE at the baseline visit and again 6months after starting TPM treatment. The parents reported the seizure frequency at both assessment dates. Statistically significant improvements in all K-QOLCE domains except social functioning were found at 6months after starting TPM treatment from the baseline-scores (P<0.05). However, improved QOL scores were not dependent on the reduction in seizure frequency. TPM significantly improved QOL in children with epilepsy, suggesting its potential clinical benefits. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 707~712 | - |
dc.relation.isPartOf | BRAIN & DEVELOPMENT | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Anticonvulsants/therapeutic use* | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Epilepsy/drug therapy* | - |
dc.subject.MESH | Epilepsy/psychology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fructose/analogs & derivatives* | - |
dc.subject.MESH | Fructose/therapeutic use | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Quality of Life* | - |
dc.subject.MESH | Surveys and Questionnaires | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Topiramate on the quality of life in childhood epilepsy. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Da-Eun Jung | - |
dc.contributor.googleauthor | Heung-Dong Kim | - |
dc.contributor.googleauthor | Yun-Jung Hur | - |
dc.contributor.googleauthor | So-Yong Eom | - |
dc.contributor.googleauthor | Korean Pediatric Topiramate Study Group | - |
dc.identifier.doi | 10.1016/j.braindev.2010.11.011 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01208 | - |
dc.relation.journalcode | J00386 | - |
dc.identifier.eissn | 1872-7131 | - |
dc.identifier.pmid | 21194859 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0387760410002986 | - |
dc.subject.keyword | Childhood epilepsy | - |
dc.subject.keyword | Quality of life | - |
dc.subject.keyword | Topiramate | - |
dc.contributor.alternativeName | Kim, Heung Dong | - |
dc.contributor.affiliatedAuthor | Kim, Heung Dong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 33 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 707 | - |
dc.citation.endPage | 712 | - |
dc.identifier.bibliographicCitation | BRAIN & DEVELOPMENT, Vol.33(9) : 707-712, 2011 | - |
dc.identifier.rimsid | 28309 | - |
dc.type.rims | ART | - |
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