Cited 7 times in
Comparison of the efficacy and toxicity between radiotherapy and chemotherapy in nodal and isolated nonnodal recurrence of ovarian cancer
DC Field | Value | Language |
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dc.contributor.author | 김귀언 | - |
dc.contributor.author | 김상운 | - |
dc.contributor.author | 김성훈 | - |
dc.contributor.author | 김영태 | - |
dc.contributor.author | 김재훈 | - |
dc.contributor.author | 남은지 | - |
dc.contributor.author | 백지흠 | - |
dc.contributor.author | 이마리아 | - |
dc.contributor.author | 이산희 | - |
dc.contributor.author | 임가원 | - |
dc.date.accessioned | 2014-12-20T16:49:40Z | - |
dc.date.available | 2014-12-20T16:49:40Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1048-891X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93453 | - |
dc.description.abstract | OBJECTIVES: To assess and compare the efficacy and toxicity of radiotherapy (RT) versus chemotherapy (CT) in patients with nodal and isolated nonnodal recurrence of ovarian cancer. METHODS: Records of 67 patients treated for nodal or isolated nonnodal ovarian cancer recurrence (50 treated with RT and 17 treated with CT) between 2001 and 2010 were retrospectively reviewed. Patients' responses to RT and CT were assessed by the Response Evaluation Criteria in Solid Tumors, and toxicity was evaluated according to the National Cancer Institute Common Toxicity Criteria, version 3.0. Progression-free survival and overall survival were calculated using the Kaplan-Meier method. RESULTS: The overall response rate was 64.0% in the RT group and 16.7% in the CT group (P = 0.003). The median follow-up time was 38 months (range, 3-97 months) for RT and 18 months (range, 70-64 months) for CT. The median progression-free survival was 6 months for radiotherapy and 5 months for chemotherapy (P = 0.212). Median overall survival between the 2 groups was not significantly different (P = 0.246). There was no RT-mediated grade 3 or 4 hematologic toxicity, but overall toxicity was not significantly different between the 2 groups. CONCLUSIONS: Radiotherapy resulted in a better response and tolerable toxicities compared to CT in patients with either nodal or isolated nonnodal ovarian cancer recurrence. However, progression-free survival and overall survival did not differ between RT and CT. A prospective, multicenter, randomized controlled study is needed to evaluate the survival benefits of RT for ovarian cancer. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1032~1039 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma, Clear Cell/mortality | - |
dc.subject.MESH | Adenocarcinoma, Clear Cell/pathology | - |
dc.subject.MESH | Adenocarcinoma, Clear Cell/therapy | - |
dc.subject.MESH | Adenocarcinoma, Mucinous/mortality | - |
dc.subject.MESH | Adenocarcinoma, Mucinous/pathology | - |
dc.subject.MESH | Adenocarcinoma, Mucinous/therapy | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Carcinoma, Endometrioid/mortality | - |
dc.subject.MESH | Carcinoma, Endometrioid/pathology | - |
dc.subject.MESH | Carcinoma, Endometrioid/therapy | - |
dc.subject.MESH | Combined Modality Therapy | - |
dc.subject.MESH | Cystadenocarcinoma, Serous/mortality | - |
dc.subject.MESH | Cystadenocarcinoma, Serous/pathology | - |
dc.subject.MESH | Cystadenocarcinoma, Serous/therapy | - |
dc.subject.MESH | Dose Fractionation | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lymphatic Metastasis | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Recurrence, Local/mortality | - |
dc.subject.MESH | Neoplasm Recurrence, Local/pathology | - |
dc.subject.MESH | Neoplasm Recurrence, Local/therapy* | - |
dc.subject.MESH | Ovarian Neoplasms/mortality | - |
dc.subject.MESH | Ovarian Neoplasms/pathology | - |
dc.subject.MESH | Ovarian Neoplasms/therapy* | - |
dc.subject.MESH | Radiotherapy | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Survival Analysis | - |
dc.title | Comparison of the efficacy and toxicity between radiotherapy and chemotherapy in nodal and isolated nonnodal recurrence of ovarian cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiation Oncology (방사선종양학) | - |
dc.contributor.googleauthor | Maria Lee | - |
dc.contributor.googleauthor | Sang Wun Kim | - |
dc.contributor.googleauthor | San Hui Lee | - |
dc.contributor.googleauthor | Jiheum Paek | - |
dc.contributor.googleauthor | Ga Won Yim | - |
dc.contributor.googleauthor | Gwi Eon Kim | - |
dc.contributor.googleauthor | Sunghoon Kim | - |
dc.contributor.googleauthor | Jae Hoon Kim | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.contributor.googleauthor | Eun Ji Nam | - |
dc.identifier.doi | 10.1097/IGC.0b013e31821e0353 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00595 | - |
dc.contributor.localId | A00321 | - |
dc.contributor.localId | A00526 | - |
dc.contributor.localId | A00729 | - |
dc.contributor.localId | A00876 | - |
dc.contributor.localId | A01262 | - |
dc.contributor.localId | A01840 | - |
dc.contributor.localId | A02748 | - |
dc.contributor.localId | A02808 | - |
dc.contributor.localId | A03354 | - |
dc.relation.journalcode | J01115 | - |
dc.identifier.eissn | 1525-1438 | - |
dc.identifier.pmid | 21738040 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00009577-201108000-00012&LSLINK=80&D=ovft | - |
dc.subject.keyword | Ovarian cancer | - |
dc.subject.keyword | Nodal recurrence | - |
dc.subject.keyword | Isolated recurrence | - |
dc.subject.keyword | Radiotherapy | - |
dc.subject.keyword | Chemotherapy | - |
dc.contributor.alternativeName | Kim, Gwi Eon | - |
dc.contributor.alternativeName | Kim, Sang Wun | - |
dc.contributor.alternativeName | Kim, Sung Hoon | - |
dc.contributor.alternativeName | Kim, Young Tae | - |
dc.contributor.alternativeName | Kim, Jae Hoon | - |
dc.contributor.alternativeName | Nam, Eun Ji | - |
dc.contributor.alternativeName | Paek, Ji Heum | - |
dc.contributor.alternativeName | Lee, Maria | - |
dc.contributor.alternativeName | Lee, San Hui | - |
dc.contributor.alternativeName | Yim, Ga Won | - |
dc.contributor.affiliatedAuthor | Kim, Sung Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Gwi Eon | - |
dc.contributor.affiliatedAuthor | Kim, Sang Wun | - |
dc.contributor.affiliatedAuthor | Kim, Young Tae | - |
dc.contributor.affiliatedAuthor | Kim, Jae Hoon | - |
dc.contributor.affiliatedAuthor | Nam, Eun Ji | - |
dc.contributor.affiliatedAuthor | Paek, Ji Heum | - |
dc.contributor.affiliatedAuthor | Lee, Maria | - |
dc.contributor.affiliatedAuthor | Lee, San Hui | - |
dc.contributor.affiliatedAuthor | Yim, Ga Won | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 21 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1032 | - |
dc.citation.endPage | 1039 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol.21(6) : 1032-1039, 2011 | - |
dc.identifier.rimsid | 28243 | - |
dc.type.rims | ART | - |
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