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Epidermolysis bullosa acquisita: a retrospective clinical analysis of 30 cases

DC FieldValueLanguage
dc.contributor.author김수찬-
dc.contributor.author김종훈-
dc.date.accessioned2014-12-20T16:43:26Z-
dc.date.available2014-12-20T16:43:26Z-
dc.date.issued2011-
dc.identifier.issn0001-5555-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/93256-
dc.description.abstractEpidermolysis bullosa acquisita (EBA) is an acquired, autoimmune blistering disorder caused by autoantibody production against type VII collagen. The aim of this study was to examine the clinical types, treatments, and outcomes of 30 patients with EBA. In our cohort, the median age of onset was 44.0 years, with a similar incidence for both genders (46.7% male, 53.3% female). The majority of patients had classic type (36.7%) and bullous pemphigoid (BP)-like type (46.7%) EBA. The remaining patients had mucous membrane pemphigoid-like (6.7%), Brunsting-Perry pemphigoid-like (6.7%), and linear IgA bullous dermatosis-like type (3.3%) EBA. All patients were treated initially with a combination of methylprednisolone, dapsone and colchicine. No significant differences in time to remission were identified between patients with classic vs. BP-like EBA. In a second subset analysis of 19 patients, a group treated with high-dose (> 8 mg) methylprednisolone achieved remission earlier (median time to remission: 3 months) than a group treated with low-dose (≤ 8 mg) methylprednisolone (median time to remission: 12 months), irrespective of clinical type (p = 0.003).-
dc.description.statementOfResponsibilityopen-
dc.format.extent307~312-
dc.relation.isPartOfACTA DERMATO-VENEREOLOGICA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHColchicine/administration & dosage-
dc.subject.MESHDapsone/administration & dosage-
dc.subject.MESHDrug Therapy, Combination-
dc.subject.MESHEpidermolysis Bullosa Acquisita*/classification-
dc.subject.MESHEpidermolysis Bullosa Acquisita*/diagnosis-
dc.subject.MESHEpidermolysis Bullosa Acquisita*/drug therapy-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImmunosuppressive Agents/administration & dosage-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMale-
dc.subject.MESHMethylprednisolone/administration & dosage-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRemission Induction-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHYoung Adult-
dc.titleEpidermolysis bullosa acquisita: a retrospective clinical analysis of 30 cases-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Dermatology (피부과학)-
dc.contributor.googleauthorJong Hoon Kim-
dc.contributor.googleauthorYeon Hee Kim-
dc.contributor.googleauthorSoo-Chan Kim-
dc.identifier.doi10.2340/00015555-1065-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00637-
dc.contributor.localIdA05233-
dc.relation.journalcodeJ00012-
dc.identifier.eissn1651-2057-
dc.identifier.pmid21394418-
dc.subject.keywordClinical study remission-
dc.subject.keywordepidermolysis bullosa acquisita-
dc.subject.keywordretrospective study-
dc.contributor.alternativeNameKim, Soo Chan-
dc.contributor.affiliatedAuthorKim, Soo Chan-
dc.contributor.affiliatedAuthorKim, Jong Hoon-
dc.rights.accessRightsfree-
dc.citation.volume91-
dc.citation.number3-
dc.citation.startPage307-
dc.citation.endPage312-
dc.identifier.bibliographicCitationACTA DERMATO-VENEREOLOGICA, Vol.91(3) : 307-312, 2011-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers

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