Cited 77 times in
Epidermolysis bullosa acquisita: a retrospective clinical analysis of 30 cases
DC Field | Value | Language |
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dc.contributor.author | 김수찬 | - |
dc.contributor.author | 김종훈 | - |
dc.date.accessioned | 2014-12-20T16:43:26Z | - |
dc.date.available | 2014-12-20T16:43:26Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0001-5555 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93256 | - |
dc.description.abstract | Epidermolysis bullosa acquisita (EBA) is an acquired, autoimmune blistering disorder caused by autoantibody production against type VII collagen. The aim of this study was to examine the clinical types, treatments, and outcomes of 30 patients with EBA. In our cohort, the median age of onset was 44.0 years, with a similar incidence for both genders (46.7% male, 53.3% female). The majority of patients had classic type (36.7%) and bullous pemphigoid (BP)-like type (46.7%) EBA. The remaining patients had mucous membrane pemphigoid-like (6.7%), Brunsting-Perry pemphigoid-like (6.7%), and linear IgA bullous dermatosis-like type (3.3%) EBA. All patients were treated initially with a combination of methylprednisolone, dapsone and colchicine. No significant differences in time to remission were identified between patients with classic vs. BP-like EBA. In a second subset analysis of 19 patients, a group treated with high-dose (> 8 mg) methylprednisolone achieved remission earlier (median time to remission: 3 months) than a group treated with low-dose (≤ 8 mg) methylprednisolone (median time to remission: 12 months), irrespective of clinical type (p = 0.003). | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 307~312 | - |
dc.relation.isPartOf | ACTA DERMATO-VENEREOLOGICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Colchicine/administration & dosage | - |
dc.subject.MESH | Dapsone/administration & dosage | - |
dc.subject.MESH | Drug Therapy, Combination | - |
dc.subject.MESH | Epidermolysis Bullosa Acquisita*/classification | - |
dc.subject.MESH | Epidermolysis Bullosa Acquisita*/diagnosis | - |
dc.subject.MESH | Epidermolysis Bullosa Acquisita*/drug therapy | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunosuppressive Agents/administration & dosage | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Methylprednisolone/administration & dosage | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Remission Induction | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Young Adult | - |
dc.title | Epidermolysis bullosa acquisita: a retrospective clinical analysis of 30 cases | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Dermatology (피부과학) | - |
dc.contributor.googleauthor | Jong Hoon Kim | - |
dc.contributor.googleauthor | Yeon Hee Kim | - |
dc.contributor.googleauthor | Soo-Chan Kim | - |
dc.identifier.doi | 10.2340/00015555-1065 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00637 | - |
dc.contributor.localId | A05233 | - |
dc.relation.journalcode | J00012 | - |
dc.identifier.eissn | 1651-2057 | - |
dc.identifier.pmid | 21394418 | - |
dc.subject.keyword | Clinical study remission | - |
dc.subject.keyword | epidermolysis bullosa acquisita | - |
dc.subject.keyword | retrospective study | - |
dc.contributor.alternativeName | Kim, Soo Chan | - |
dc.contributor.affiliatedAuthor | Kim, Soo Chan | - |
dc.contributor.affiliatedAuthor | Kim, Jong Hoon | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 91 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 307 | - |
dc.citation.endPage | 312 | - |
dc.identifier.bibliographicCitation | ACTA DERMATO-VENEREOLOGICA, Vol.91(3) : 307-312, 2011 | - |
dc.identifier.rimsid | 27095 | - |
dc.type.rims | ART | - |
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