Cited 14 times in
Tumor margin histology predicts tumor aggressiveness in papillary thyroid carcinoma: a study of 514 consecutive patients
DC Field | Value | Language |
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dc.contributor.author | 홍순원 | - |
dc.contributor.author | 김국진 | - |
dc.contributor.author | 김법우 | - |
dc.contributor.author | 박정수 | - |
dc.contributor.author | 이승철 | - |
dc.contributor.author | 이용상 | - |
dc.contributor.author | 장항석 | - |
dc.date.accessioned | 2014-12-20T16:41:13Z | - |
dc.date.available | 2014-12-20T16:41:13Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93185 | - |
dc.description.abstract | Histologic patterns at tumor margins may be related to prognosis in several malignancies. We investigated tumor aggressiveness with respect to tumor margin histology in patients with papillary thyroid carcinoma (PTC). Five hundred fourteen consecutive patients who underwent surgery for primary PTC between January and July 2009 were assigned to two groups, one with an infiltrative pattern (I-type, n = 347) at tumor margins and one with an expanding pattern (E-type, n = 167). Tumor aggressiveness was assessed by analyzing relationships between these patterns and known prognostic factors. The analysis showed that unfavorable prognostic factors such as tumor multiplicity (P = 0.002), extrathyroidal extension (P < 0.001), lateral neck lymph node metastasis (P < 0.001) and advanced TNM stage (P = 0.001) were significantly more prevalent in patients with I-type PTC than in those with the E-type. Central neck node metastases were more prevalent without statistical significance in the I-type patients (P = 0.376). Tumor margin histology was not related to gender or tumor size. These results suggest that histologic patterns at tumor margins predict aggressiveness in PTC. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 346~351 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Carcinoma | - |
dc.subject.MESH | Carcinoma, Papillary | - |
dc.subject.MESH | Cell Proliferation | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lymphatic Metastasis | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Invasiveness | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Thyroid Neoplasms/epidemiology | - |
dc.subject.MESH | Thyroid Neoplasms/pathology* | - |
dc.title | Tumor margin histology predicts tumor aggressiveness in papillary thyroid carcinoma: a study of 514 consecutive patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학) | - |
dc.contributor.googleauthor | Kuk-Jin Kim | - |
dc.contributor.googleauthor | Soon Won Hong | - |
dc.contributor.googleauthor | Yong Sang Lee | - |
dc.contributor.googleauthor | Bup-Woo Kim | - |
dc.contributor.googleauthor | Seung Chul Lee | - |
dc.contributor.googleauthor | Hang-Seok Chang | - |
dc.contributor.googleauthor | Cheong Soo Park | - |
dc.identifier.doi | 10.3346/jkms.2011.26.3.346 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02929 | - |
dc.contributor.localId | A01646 | - |
dc.contributor.localId | A04411 | - |
dc.contributor.localId | A00320 | - |
dc.contributor.localId | A00491 | - |
dc.contributor.localId | A02978 | - |
dc.contributor.localId | A03488 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 21394301 | - |
dc.subject.keyword | Aggressiveness | - |
dc.subject.keyword | Carcinoma, Papillary | - |
dc.subject.keyword | Histology | - |
dc.subject.keyword | Margin | - |
dc.subject.keyword | Thyroid | - |
dc.contributor.alternativeName | Hong, Soon Won | - |
dc.contributor.alternativeName | Kim, Kuk Jin | - |
dc.contributor.alternativeName | Kim, Bup Woo | - |
dc.contributor.alternativeName | Park, Cheong Soo | - |
dc.contributor.alternativeName | Lee, Seung Chul | - |
dc.contributor.alternativeName | Lee, Yong Sang | - |
dc.contributor.alternativeName | Chang, Hang Seok | - |
dc.contributor.affiliatedAuthor | Lee, Seung Chul | - |
dc.contributor.affiliatedAuthor | Park, Cheong Soo | - |
dc.contributor.affiliatedAuthor | Hong, Soon Won | - |
dc.contributor.affiliatedAuthor | Kim, Kuk Jin | - |
dc.contributor.affiliatedAuthor | Kim, Bup Woo | - |
dc.contributor.affiliatedAuthor | Lee, Yong Sang | - |
dc.contributor.affiliatedAuthor | Chang, Hang Seok | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 26 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 346 | - |
dc.citation.endPage | 351 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.26(3) : 346-351, 2011 | - |
dc.identifier.rimsid | 27043 | - |
dc.type.rims | ART | - |
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