3 279

Cited 51 times in

Factors affecting inadequate sampling of ultrasound-guided fine-needle aspiration biopsy of thyroid nodules.

 Seon Hyeong Choi  ;  Kyung Hwa Han  ;  Jung Hyun Yoon  ;  Hee Jung Moon  ;  Eun Ju Son  ;  Ji Hyun Youk  ;  Eun-Kyung Kim  ;  Jin Young Kwak 
 CLINICAL ENDOCRINOLOGY, Vol.74(6) : 776-782, 2011 
Journal Title
Issue Date
Adult ; Biopsy, Fine-Needle/methods* ; Biopsy, Fine-Needle/standards ; Diagnosis, Differential ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Reproducibility of Results ; Sensitivity and Specificity ; Thyroid Gland/diagnostic imaging* ; Thyroid Gland/pathology ; Thyroid Nodule/diagnostic imaging* ; Thyroid Nodule/pathology ; Ultrasonography/methods*
PURPOSE: The aim of this study was to evaluate the overall ultrasonographic features and clinical factors that contribute to inadequate sampling in ultrasound-guided fine-needle aspiration biopsy (US-FNAB) of thyroid nodules. MATERIALS AND METHODS: From April 2008 to December 2008, 4077 US-FNABs in 3767 consecutive patients were reviewed. We evaluated the clinical, ultrasound and pathological features of patients and analysed the association between these features and inadequate samples. We also compared inadequate sample rates according to the experience of the performing doctor. RESULTS: The inadequate sample rate was 16·1% (654/4077). Univariate analysis revealed an association between inadequate samples and cyst dominancy, macrocalcification and benign pathology of the nodule. The inadequate sample rate was also higher in the inexperienced group than in the experienced group. In multivariate analysis, cyst dominancy and macrocalcification of a nodule were significantly associated with inadequate samples in the experienced group. CONCLUSION: Cyst dominancy and macrocalcifications in thyroid nodules, inexperience of the performing doctor and benign pathology were factors associated with high inadequate sample rates of US-FNAB in thyroid nodules.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Jin Young(곽진영) ORCID logo https://orcid.org/0000-0002-6212-1495
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Moon, Hee Jung(문희정) ORCID logo https://orcid.org/0000-0002-5643-5885
Son, Eun Ju(손은주) ORCID logo https://orcid.org/0000-0002-7895-0335
Youk, Ji Hyun(육지현) ORCID logo https://orcid.org/0000-0002-7787-780X
Yoon, Jung Hyun(윤정현) ORCID logo https://orcid.org/0000-0002-2100-3513
Choi, Seon Hyeong(최성형)
Han, Kyung Hwa(한경화)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.