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Prescription pattern of NSAIDs and the prevalence of NSAID-induced gastrointestinal risk factors of orthopaedic patients in clinical practice in Korea

DC FieldValueLanguage
dc.contributor.author양익환-
dc.contributor.author한창동-
dc.date.accessioned2014-12-20T16:36:11Z-
dc.date.available2014-12-20T16:36:11Z-
dc.date.issued2011-
dc.identifier.issn1011-8934-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/93027-
dc.description.abstractThis is a cross-sectional observational study undertaken to explore the current prescription pattern of non-steroidal anti-inflammatory drugs (NSAIDs) and the prevalence of NSAID-induced gastrointestinal (GI) risk factors of orthopaedic patients in real clinical practice in Korea. Study cohort included 3,140 orthopaedic outpatients at 131 hospitals and clinics between January 2008 and August 2008. A self-administered questionnaire was completed by each patient and physician. A simplified risk scoring scale (the Standardized Calculator of Risk for Events; SCORE) was used to measure patients' risk for GI complications. The pattern of NSAIDs prescription was identified from medical recordings. Forty-five percent of the patients belonged to high risk or very high risk groups for GI complications. The cyclooxygenase-2 enzyme (COX-2) selective NSAID showed a propensity to be prescribed more commonly for high/very high GI risk groups, but the rate was still as low as 51%. In conclusion, physician's considerate prescription of NSAIDs with well-understanding of each patient's GI risk factors is strongly encouraged in order to maximize cost effectiveness and to prevent serious GI complications in Korea. Other strategic efforts such as medical association-led education programs and application of Korean electronic SCORE system to hospital order communication system (OCS) should also be accompanied in a way to promote physician's attention-
dc.description.statementOfResponsibilityopen-
dc.format.extent561~567-
dc.relation.isPartOfJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAnti-Inflammatory Agents, Non-Steroidal/adverse effects*-
dc.subject.MESHCohort Studies-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHCyclooxygenase 2/metabolism-
dc.subject.MESHCyclooxygenase 2 Inhibitors/adverse effects-
dc.subject.MESHDrug Prescriptions-
dc.subject.MESHFemale-
dc.subject.MESHGastrointestinal Diseases/chemically induced-
dc.subject.MESHGastrointestinal Diseases/complications-
dc.subject.MESHGastrointestinal Diseases/epidemiology*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMusculoskeletal Diseases/complications-
dc.subject.MESHMusculoskeletal Diseases/drug therapy*-
dc.subject.MESHPrevalence-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRisk Factors-
dc.subject.MESHSurveys and Questionnaires-
dc.titlePrescription pattern of NSAIDs and the prevalence of NSAID-induced gastrointestinal risk factors of orthopaedic patients in clinical practice in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Orthopedic Surgery (정형외과학)-
dc.contributor.googleauthorSung-Hun Lee-
dc.contributor.googleauthorChang-Dong Han-
dc.contributor.googleauthorIck-Hwan Yang-
dc.contributor.googleauthorChul-Won Ha-
dc.identifier.doi10.3346/jkms.2011.26.4.561-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02313-
dc.contributor.localIdA04330-
dc.relation.journalcodeJ01517-
dc.identifier.eissn1598-6357-
dc.identifier.pmid21468265-
dc.subject.keywordAnti-Inflammatory Agents, Non-Steroidal-
dc.subject.keywordCyclooxygenase 2 Inhibitors-
dc.subject.keywordGI risk factor-
dc.subject.keywordKorea-
dc.subject.keywordSCORE-
dc.contributor.alternativeNameYang, Ick Hwan-
dc.contributor.alternativeNameHan, Chang Dong-
dc.contributor.affiliatedAuthorYang, Ick Hwan-
dc.contributor.affiliatedAuthorHan, Chang Dong-
dc.rights.accessRightsfree-
dc.citation.volume26-
dc.citation.number4-
dc.citation.startPage561-
dc.citation.endPage567-
dc.identifier.bibliographicCitationJOURNAL OF KOREAN MEDICAL SCIENCE, Vol.26(4) : 561-567, 2011-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers

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