6 592

Cited 80 times in

Prognostic impact of inferior mesenteric artery lymph node metastasis in colorectal cancer

DC Field Value Language
dc.contributor.author강정현-
dc.contributor.author김남규-
dc.contributor.author민병소-
dc.contributor.author이강영-
dc.contributor.author허혁-
dc.date.accessioned2014-12-20T16:34:05Z-
dc.date.available2014-12-20T16:34:05Z-
dc.date.issued2011-
dc.identifier.issn1068-9265-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/92962-
dc.description.abstractAIM: The aims of this study are to identify the natural course of inferior mesenteric artery (IMA) lymph node metastasis, and to evaluate the prognostic impact of IMA lymph node metastasis in the sigmoid colon and rectal cancer. PATIENTS AND METHODS: From our prospectively collected database, a total of 625 patients who underwent resection with curative intent for stage III adenocarcinoma of the sigmoid colon and rectal cancer between June 1995 and June 2007 were selected. Patients were divided into the IMA-positive group (n = 33) and the IMA-negative group (n = 592) according to IMA lymph node metastasis status. Clinicopathological features, recurrence patterns, and 5-year disease-free survival rates were compared between the two groups. RESULTS: Following curative resection, 5-year disease-free survival rate was 31.9% in the IMA-positive group and 69.4% in the IMA-negative group (p < 0.001). Cox regression analysis revealed that rectal cancer, pathologic stage, and presence of IMA lymph node metastasis were independently associated with disease-free survival. Systemic recurrence rate was significantly higher in the IMA-positive group than in the IMA-negative group (48.5 vs. 20.8%, respectively, p = 0.001). Para-aortic nodal recurrence showed significant association with presence of IMA lymph node metastasis on multivariate analysis (hazard ratio 11.8; 95% confidence interval 2.7-52.2, p = 0.001). CONCLUSION: Presence of IMA lymph node metastasis should be considered as a predictive factor for high systemic recurrence, and should be treated and followed up with caution for para-aortic nodal recurrence.-
dc.description.statementOfResponsibilityopen-
dc.format.extent704~710-
dc.relation.isPartOfANNALS OF SURGICAL ONCOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdenocarcinoma/secondary-
dc.subject.MESHAdenocarcinoma/surgery-
dc.subject.MESHColon, Sigmoid/pathology*-
dc.subject.MESHColon, Sigmoid/surgery-
dc.subject.MESHColonic Neoplasms/pathology*-
dc.subject.MESHColonic Neoplasms/surgery-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLigation-
dc.subject.MESHLymphatic Metastasis-
dc.subject.MESHMale-
dc.subject.MESHMesenteric Artery, Inferior/pathology*-
dc.subject.MESHMesenteric Artery, Inferior/surgery-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Recurrence, Local/pathology*-
dc.subject.MESHNeoplasm Recurrence, Local/surgery-
dc.subject.MESHProspective Studies-
dc.subject.MESHRectal Neoplasms/pathology*-
dc.subject.MESHRectal Neoplasms/surgery-
dc.subject.MESHSigmoid Neoplasms/secondary*-
dc.subject.MESHSigmoid Neoplasms/surgery-
dc.subject.MESHSurvival Rate-
dc.subject.MESHTreatment Outcome-
dc.titlePrognostic impact of inferior mesenteric artery lymph node metastasis in colorectal cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorJeonghyun Kang-
dc.contributor.googleauthorHyuk Hur-
dc.contributor.googleauthorByung Soh Min-
dc.contributor.googleauthorNam Kyu Kim-
dc.contributor.googleauthorKang Young Lee-
dc.identifier.doi10.1245/s10434-010-1291-x-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00080-
dc.contributor.localIdA00353-
dc.contributor.localIdA01402-
dc.contributor.localIdA02640-
dc.contributor.localIdA04373-
dc.relation.journalcodeJ00179-
dc.identifier.eissn1534-4681-
dc.identifier.pmid20857225-
dc.identifier.urlhttp://link.springer.com/article/10.1245%2Fs10434-010-1291-x-
dc.subject.keywordRectal Cancer-
dc.subject.keywordSigmoid Colon-
dc.subject.keywordMetastatic Lymph Node-
dc.subject.keywordRectal Cancer Patient-
dc.subject.keywordInferior Mesenteric Artery-
dc.contributor.alternativeNameKang, Jeong Hyun-
dc.contributor.alternativeNameKim, Nam Kyu-
dc.contributor.alternativeNameMin, Byung Soh-
dc.contributor.alternativeNameLee, Kang Young-
dc.contributor.alternativeNameHur, Hyuk-
dc.contributor.affiliatedAuthorKang, Jeong Hyun-
dc.contributor.affiliatedAuthorKim, Nam Kyu-
dc.contributor.affiliatedAuthorMin, Byung Soh-
dc.contributor.affiliatedAuthorLee, Kang Young-
dc.contributor.affiliatedAuthorHur, Hyuk-
dc.rights.accessRightsnot free-
dc.citation.volume18-
dc.citation.number3-
dc.citation.startPage704-
dc.citation.endPage710-
dc.identifier.bibliographicCitationANNALS OF SURGICAL ONCOLOGY, Vol.18(3) : 704-710, 2011-
dc.identifier.rimsid27933-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.