6 769

Cited 30 times in

Neurocognitive performance in subjects at ultrahigh risk for schizophrenia: a comparison with first-episode schizophrenia

DC Field Value Language
dc.contributor.author김경란-
dc.contributor.author박진영-
dc.contributor.author송동호-
dc.contributor.author안석균-
dc.date.accessioned2014-12-20T16:25:12Z-
dc.date.available2014-12-20T16:25:12Z-
dc.date.issued2011-
dc.identifier.issn0010-440X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/92681-
dc.description.abstractOBJECTIVE: The aim of the present study was to explore the neurocognitive performance of patients at ultrahigh risk (UHR) compared with patients with first-episode (FE) schizophrenia and healthy control (HC) subjects. METHOD: Twenty-seven subjects at UHR for schizophrenia, 25 patients in their FE of schizophrenia, and 33 HCs were included. All participants completed a neurocognitive battery, including tests of general intelligence, attention and working memory, executive function, and verbal and visual memory. RESULTS: Of the 3 groups, the FE subjects performed poorest at all neurocognitive tests, encompassing the broad range of impairments. The UHR subjects had a similar pattern of neuropsychological dysfunction but less severe than that of FE patients. The UHR subjects were particularly impaired on measures of attention and working memory, executive function, and verbal memory compared with the HCs. CONCLUSION: These findings are consistent with the view that the neurocognitive impairments of schizophrenia are neurodevelopmental in nature and, although less severe, those impairments are mostly in place before the onset of the first frank psychotic episode. Neurocognitive impairments may play an important role in the pathogenesis of early psychosis and could help to clarify individuals at UHR for schizophrenia-
dc.description.statementOfResponsibilityopen-
dc.format.extent33~40-
dc.relation.isPartOfCOMPREHENSIVE PSYCHIATRY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAttention-
dc.subject.MESHCase-Control Studies-
dc.subject.MESHCognition*-
dc.subject.MESHExecutive Function-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIntelligence Tests-
dc.subject.MESHMale-
dc.subject.MESHMemory, Short-Term-
dc.subject.MESHNeuropsychological Tests-
dc.subject.MESHPsychiatric Status Rating Scales-
dc.subject.MESHRiskFactors-
dc.subject.MESHSchizophrenia/etiology-
dc.subject.MESHSchizophrenic Psychology*-
dc.subject.MESHYoung Adult-
dc.titleNeurocognitive performance in subjects at ultrahigh risk for schizophrenia: a comparison with first-episode schizophrenia-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Psychiatry (정신과학)-
dc.contributor.googleauthorKyung Ran Kim-
dc.contributor.googleauthorJin Young Park-
dc.contributor.googleauthorDong-Ho Song-
dc.contributor.googleauthorHae Kyung Koo-
dc.contributor.googleauthorSuk Kyoon An-
dc.identifier.doi10.1016/j.comppsych.2010.04.010-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01701-
dc.contributor.localIdA00293-
dc.contributor.localIdA02018-
dc.contributor.localIdA02227-
dc.relation.journalcodeJ00633-
dc.identifier.eissn1532-8384-
dc.identifier.pmid21220063-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0010440X10000441-
dc.contributor.alternativeNameKim, Kyung Ran-
dc.contributor.alternativeNamePark, Jin Young-
dc.contributor.alternativeNameSong, Dong Ho-
dc.contributor.alternativeNameAn, Suk Kyoon-
dc.contributor.affiliatedAuthorPark, Jin Young-
dc.contributor.affiliatedAuthorKim, Kyung Ran-
dc.contributor.affiliatedAuthorSong, Dong Ho-
dc.contributor.affiliatedAuthorAn, Suk Kyoon-
dc.rights.accessRightsnot free-
dc.citation.volume52-
dc.citation.number1-
dc.citation.startPage33-
dc.citation.endPage40-
dc.identifier.bibliographicCitationCOMPREHENSIVE PSYCHIATRY, Vol.52(1) : 33-40, 2011-
dc.identifier.rimsid28693-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.