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중환자에서 질병 중증도와 영양 상태가 예후에 미치는 효과

Other Titles
 Effects of APACHE II Score and Initial Nutritional Status on Prognosis of the Critically Ill Patients 
 안서희  ;  라세희  ;  장철호  ;  임현선  ;  이덕철  ;  신증수 
 Korean Journal of Critical Care Medicine, Vol.27(2) : 102-107, 2012 
Journal Title
Korean Journal of Critical Care Medicine
Issue Date
APACHE II score ; ICU patients ; malnutrition ; mortality ; nutritional status
Background: Malnutrition is common in hospitalized patients, especially in critically ill patients and affects their
mortality and morbidity. However, the correlation between malnutrition and poor outcome is not fully understood.
Our hypothesis is that the nutritional effect on the patient’s prognosis would differ depending on the severity of the
Methods: 3,758 patients admitted to the intensive care unit (ICU) were observed retrospectively. Patients were
divided into well, moderate and severe groups, according to their nutritional status as assessed by their serum albumin
level and total lymphocyte count (TLC). The severity of the disease was assessed by the Acute Physiologic
and Chronic Health Evaluation (APACHE II score). All patients were followed clinically until discharge or death
and ICU days, hospital days, ventilator days, and mortality rates were recorded.
Results: Depending on the definition used, the prevalence of hospital malnutrition is reported to be 68.3%.
Hospital days, ICU days, as well as ventilator days of moderate and severe groups were longer than the well group.
In patients exhibiting mild severity of disease, moderate and severe malnutrition groups have 3-5 times the mortality
rate than the well group.
Conclusions: Malnutrition affects the prognosis of patients who have an APACHE II score ranging from 4-29
points. Active nutritional support may be more effective for patients with a disease of mild severity.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
Yonsei Authors
Na, Se Hee(라세희) ORCID logo https://orcid.org/0000-0003-4208-0769
Shin, Cheung Soo(신증수) ORCID logo https://orcid.org/0000-0001-7829-8458
Lee, Duk Chul(이덕철) ORCID logo https://orcid.org/0000-0001-9166-1813
Chang, Chul Ho(장철호) ORCID logo https://orcid.org/0000-0001-5647-8298
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