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Spontaneous bacterial peritonitis in patients with hepatitis B virus-related liver cirrhosis: community-acquired versus nosocomial

DC Field Value Language
dc.contributor.author전영은-
dc.contributor.author전재윤-
dc.contributor.author정규식-
dc.contributor.author한광협-
dc.contributor.author김도영-
dc.contributor.author김승업-
dc.contributor.author박준용-
dc.contributor.author안상훈-
dc.date.accessioned2014-12-19T17:48:33Z-
dc.date.available2014-12-19T17:48:33Z-
dc.date.issued2012-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/92099-
dc.description.abstractPURPOSE: Spontaneous bacterial peritonitis (SBP) frequently develops in patients with liver cirrhosis; however, there is little data to suggest whether the acquisition site of infection influences the prognosis. This study compared the bacteriology, clinical characteristics and treatment outcomes of community-acquired SBP (CA-SBP) and nosocomial SBP (N-SBP). MATERIALS AND METHODS: The medical records of 130 patients with hepatitis B virus (HBV)-related liver cirrhosis, who had experienced a first episode of SBP between January 1999 and December 2008, were reviewed. RESULTS: The study population included 111 (85.4%) patients with CA-SBP and 19 (14.6%) patients with N-SBP. Baseline and microbiological characteristics as well as clinical course, including in-hospital mortality, did not differ between patients with CA-SBP and those with N-SBP (all p>0.05). The median survival time was 6.5 months, and 117 (90.0%) patients died during the follow-up period. Patients with CA-SBP and N-SBP survived for median periods of 6.6 and 6.2 months, respectively, without significant difference (p=0.569). Time to recurrence did not differ between patients with CA-SBP and N-SBP (4.7 vs. 3.6 months, p=0.925). CONCLUSION: The acquisition site of infection did not affect clinical outcomes for patients with HBV-related liver cirrhosis who had experienced their first episode of SBP. Third-generation cephalosporins may be effective in empirically treating these patients, regardless of the acquisition site of the infection.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCommunity-Acquired Infections/etiology-
dc.subject.MESHCommunity-Acquired Infections/microbiology*-
dc.subject.MESHCommunity-Acquired Infections/mortality-
dc.subject.MESHCommunity-Acquired Infections/virology-
dc.subject.MESHFemale-
dc.subject.MESHHepatitis B virus/pathogenicity*-
dc.subject.MESHHumans-
dc.subject.MESHLiver Cirrhosis/complications-
dc.subject.MESHLiver Cirrhosis/mortality-
dc.subject.MESHLiver Cirrhosis/virology*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPeritonitis/etiology-
dc.subject.MESHPeritonitis/microbiology*-
dc.subject.MESHPeritonitis/mortality-
dc.subject.MESHPeritonitis/virology*-
dc.subject.MESHRetrospective Studies-
dc.titleSpontaneous bacterial peritonitis in patients with hepatitis B virus-related liver cirrhosis: community-acquired versus nosocomial-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSeung Up Kim-
dc.contributor.googleauthorYoung Eun Chon-
dc.contributor.googleauthorChun Kyon Lee-
dc.contributor.googleauthorJun Yong Park-
dc.contributor.googleauthorDo Young Kim-
dc.contributor.googleauthorKwang-Hyub Han-
dc.contributor.googleauthorChae Yoon Chon-
dc.contributor.googleauthorSinyoung Kim-
dc.contributor.googleauthorKyu Sik Jung-
dc.contributor.googleauthorSang Hoon Ahn-
dc.identifier.doi22318820-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03532-
dc.contributor.localIdA03578-
dc.contributor.localIdA04268-
dc.contributor.localIdA00654-
dc.contributor.localIdA01675-
dc.contributor.localIdA02226-
dc.contributor.localIdA03544-
dc.contributor.localIdA00385-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid22318820-
dc.subject.keywordAscites-
dc.subject.keywordcirrhosis-
dc.subject.keywordcommunity-acquired-
dc.subject.keywordnosocomial-
dc.subject.keywordspontaneous bacterial peritonitis-
dc.contributor.alternativeNameChon, Young Eun-
dc.contributor.alternativeNameChon, Chae Yoon-
dc.contributor.alternativeNameJung, Kyu Sik-
dc.contributor.alternativeNameHan, Kwang Hyup-
dc.contributor.alternativeNameKim, Do Young-
dc.contributor.alternativeNameKim, Seung Up-
dc.contributor.alternativeNamePark, Jun Yong-
dc.contributor.alternativeNameAhn, Sang Hoon-
dc.contributor.affiliatedAuthorChon, Young Eun-
dc.contributor.affiliatedAuthorJung, Kyu Sik-
dc.contributor.affiliatedAuthorHan, Kwang Hyup-
dc.contributor.affiliatedAuthorKim, Seung Up-
dc.contributor.affiliatedAuthorPark, Jun Yong-
dc.contributor.affiliatedAuthorAhn, Sang Hoon-
dc.contributor.affiliatedAuthorChon, Chae Yoon-
dc.contributor.affiliatedAuthorKim, Do Young-
dc.citation.volume53-
dc.citation.number2-
dc.citation.startPage328-
dc.citation.endPage336-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.53(2) : 328-336, 2012-
dc.identifier.rimsid29615-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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