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Outcome after gastrectomy in gastric cancer patients with type 2 diabetes

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dc.contributor.author김종원-
dc.contributor.author노성훈-
dc.contributor.author정재호-
dc.contributor.author최승호-
dc.contributor.author형우진-
dc.date.accessioned2014-12-19T17:45:56Z-
dc.date.available2014-12-19T17:45:56Z-
dc.date.issued2012-
dc.identifier.issn1007-9327-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/92015-
dc.description.abstractAIM: To evaluate the prognosis of type II diabetes mellitus (T2DM) after gastrectomy and related factors in gastric cancer patients. METHODS: 403 gastric cancer patients with T2DM were studied, who underwent gastrectomy between May 2003 and September 2009. A review of medical records and telephone interviews was performed in this cross-sectional study. The factors included in the statistical analysis were as follows: gender, age, type of surgery, preoperative body mass index (BMI), current BMI, BMI reduction ratio, preoperative insulin or oral diabetic medicine requirement, follow-up duration, and current state of diabetes. Assessment of diabetes status after surgery was classified into four categories according to the change in hypoglycemic agents after surgery and present status of T2DM: resolution, improvement, same, and worse. RESULTS: The mean follow-up duration was 33.7 mo (± 20.6 mo), preoperative BMI was 24.7 kg/m(2) (± 3.0 kg/m(2)), and BMI reduction ratio was 9.8% (± 8.6%). After surgery, T2DM was cured in 58 patients (15.1%) and was improved in 117 patients (30.4%). According to the type of surgery, the BMI reduction ratio was significantly higher in the total gastrectomy and Roux-en-Y reconstruction group [14.2% ± 9.2% vs 9.2% ± 7.7% (Billroth II group), P < 0.001] and significantly lower in the subtotal gastrectomy and Billroth I reconstruction group [7.6% ± 8.0%, 9.2% ± 7.7% (Billroth II group), P < 0.001]. The BMI reduction ratio, follow-up duration after surgery, type of surgery, extent of gastrectomy, and performance of duodenal bypass were significantly correlated to the course of T2DM (P < 0.05). The BMI reduction ratio was the most influential factor on T2DM status. In a subgroup analysis of patients with a BMI reduction ratio of 10% or less (n = 206), T2DM was cured in 15 (7.6%) patients and was improved in 57 (28.8%) patients after surgery, and only the duration of surgery was significantly correlated to T2DM status (P = 0.022). CONCLUSION: The course of T2DM was significantly correlated to the BMI reduction ratio but not to the type of surgery without a significant change in BMI.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfWORLD JOURNAL OF GASTROENTEROLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBody Mass Index-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHDiabetes Mellitus, Type 2/diagnosis-
dc.subject.MESHDiabetes Mellitus, Type 2/physiopathology-
dc.subject.MESHDiabetes Mellitus, Type 2/surgery*-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGastrectomy/methods*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHObesity, Morbid/surgery-
dc.subject.MESHPrognosis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHStomach Neoplasms/surgery*-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHWeight Loss-
dc.titleOutcome after gastrectomy in gastric cancer patients with type 2 diabetes-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorJong Won Kim-
dc.contributor.googleauthorJae-Ho Cheong-
dc.contributor.googleauthorWoo Jin Hyung-
dc.contributor.googleauthorSeung-Ho Choi-
dc.contributor.googleauthorSung Hoon Noh-
dc.identifier.doi22228970-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04102-
dc.contributor.localIdA00925-
dc.contributor.localIdA01281-
dc.contributor.localIdA03717-
dc.contributor.localIdA04382-
dc.relation.journalcodeJ02795-
dc.identifier.eissn2219-2840-
dc.identifier.pmid22228970-
dc.subject.keywordBariatric surgery-
dc.subject.keywordDiabetes mellitus-
dc.subject.keywordGastric cancer-
dc.subject.keywordMetabolic surgery-
dc.contributor.alternativeNameKim, Jong Won-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNameCheong, Jae Ho-
dc.contributor.alternativeNameChoi, Seung Ho-
dc.contributor.alternativeNameHyung, Woo Jin-
dc.contributor.affiliatedAuthorChoi, Seung Ho-
dc.contributor.affiliatedAuthorKim, Jong Won-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorCheong, Jae Ho-
dc.contributor.affiliatedAuthorHyung, Woo Jin-
dc.citation.volume18-
dc.citation.number1-
dc.citation.startPage49-
dc.citation.endPage54-
dc.identifier.bibliographicCitationWORLD JOURNAL OF GASTROENTEROLOGY, Vol.18(1) : 49-54, 2012-
dc.identifier.rimsid30074-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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