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Implications of clinical risk score to predict outcomes of liver-confined metastasis of colorectal cancer
DC Field | Value | Language |
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dc.contributor.author | 김남규 | - |
dc.contributor.author | 노재경 | - |
dc.contributor.author | 민병소 | - |
dc.contributor.author | 백승혁 | - |
dc.contributor.author | 신상준 | - |
dc.contributor.author | 안중배 | - |
dc.contributor.author | 이강영 | - |
dc.contributor.author | 최기홍 | - |
dc.contributor.author | 최진섭 | - |
dc.contributor.author | 허혁 | - |
dc.date.accessioned | 2014-12-19T17:42:42Z | - |
dc.date.available | 2014-12-19T17:42:42Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0960-7404 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/91910 | - |
dc.description.abstract | OBJECTIVE/BACKGROUND: We investigated the usefulness of a clinical risk scoring system (CRS) for guiding management and defining prognosis for patients with colorectal liver met"astases (CLM). METHOD: We retrospectively analyzed data about the correlation between outcomes and Fong's CRS from 1989 to 2010 for patients treated for CLM at the Severance Hospital. RESULTS: Of 566 patients, 232 received adjuvant treatment after liver resection. Of these patients, 185 (81%) had a low CRS (0-2) and 47 (19%) had a high CRS (3-5). Stratification into high and low CRS allowed significant distinction between Kaplan-Meier curves for outcome. The 5-year survival rate was 88.5% and 11.5% among patients with a low and high CRS, respectively (P < 0.001). Seventy patients with initially unresectable CLM underwent liver resection after tumor downsizing by induction chemotherapy. Shifting of the CRS from high to low (8 patients; 11.4%) improved disease-free survival and overall survival. CONCLUSION: High CRS is associated with worse survival after resection in resectable and unresectable disease. The CRS may be used for risk assessment when recommending oncological surgical timing in initially unresectable disease and treatment options for perioperative or adjuvant treatment in resectable disease. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | SURGICAL ONCOLOGY-OXFORD | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Antineoplastic Combined Chemotherapy Protocols/therapeutic use | - |
dc.subject.MESH | Catheter Ablation/methods | - |
dc.subject.MESH | Catheter Ablation/mortality | - |
dc.subject.MESH | Colorectal Neoplasms* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Liver Neoplasms/secondary* | - |
dc.subject.MESH | Liver Neoplasms/surgery | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoadjuvant Therapy/mortality | - |
dc.subject.MESH | Neoplasm Recurrence, Local/mortality | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Young Adult | - |
dc.title | Implications of clinical risk score to predict outcomes of liver-confined metastasis of colorectal cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Sang Joon Shin | - |
dc.contributor.googleauthor | Joong Bae Ahn | - |
dc.contributor.googleauthor | Jin Sub Choi | - |
dc.contributor.googleauthor | Gi-Hong Choi | - |
dc.contributor.googleauthor | Kang Young Lee | - |
dc.contributor.googleauthor | Seung Hyuk Baik | - |
dc.contributor.googleauthor | Byung Soh Min | - |
dc.contributor.googleauthor | Hyuk Hur | - |
dc.contributor.googleauthor | Jae Kyung Roh | - |
dc.contributor.googleauthor | Nam Kyu Kim | - |
dc.identifier.doi | 22560405 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00353 | - |
dc.contributor.localId | A01290 | - |
dc.contributor.localId | A01402 | - |
dc.contributor.localId | A01827 | - |
dc.contributor.localId | A02105 | - |
dc.contributor.localId | A02262 | - |
dc.contributor.localId | A02640 | - |
dc.contributor.localId | A04046 | - |
dc.contributor.localId | A04199 | - |
dc.contributor.localId | A04373 | - |
dc.relation.journalcode | J02709 | - |
dc.identifier.eissn | 1879-3320 | - |
dc.identifier.pmid | 22560405 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0960740412000254 | - |
dc.subject.keyword | Colorectal cancer | - |
dc.subject.keyword | Liver metastasis | - |
dc.subject.keyword | Clinical risk score | - |
dc.subject.keyword | Treatment decision | - |
dc.subject.keyword | Multidisciplinary | - |
dc.contributor.alternativeName | Kim, Nam Kyu | - |
dc.contributor.alternativeName | Roh, Jae Kyung | - |
dc.contributor.alternativeName | Min, Byung Soh | - |
dc.contributor.alternativeName | Baik, Seung Hyuk | - |
dc.contributor.alternativeName | Shin, Sang Joon | - |
dc.contributor.alternativeName | Ahn, Joong Bae | - |
dc.contributor.alternativeName | Lee, Kang Young | - |
dc.contributor.alternativeName | Choi, Gi Hong | - |
dc.contributor.alternativeName | Choi, Jin Sub | - |
dc.contributor.alternativeName | Hur, Hyuk | - |
dc.contributor.affiliatedAuthor | Kim, Nam Kyu | - |
dc.contributor.affiliatedAuthor | Roh, Jae Kyung | - |
dc.contributor.affiliatedAuthor | Min, Byung Soh | - |
dc.contributor.affiliatedAuthor | Baik, Seung Hyuk | - |
dc.contributor.affiliatedAuthor | Shin, Sang Joon | - |
dc.contributor.affiliatedAuthor | Ahn, Joong Bae | - |
dc.contributor.affiliatedAuthor | Lee, Kang Young | - |
dc.contributor.affiliatedAuthor | Choi, Gi Hong | - |
dc.contributor.affiliatedAuthor | Choi, Jin Sub | - |
dc.contributor.affiliatedAuthor | Hur, Hyuk | - |
dc.citation.volume | 21 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 125 | - |
dc.citation.endPage | 130 | - |
dc.identifier.bibliographicCitation | SURGICAL ONCOLOGY-OXFORD, Vol.21(3) : 125-130, 2012 | - |
dc.identifier.rimsid | 30001 | - |
dc.type.rims | ART | - |
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